{"id":"W2049215013","doi":"10.1038/cdd.2014.37","title":"Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells","year":2014,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"KWF Kankerbestrijding; University of Toronto; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Cancer stem cell; Priming (agriculture); Chemotherapy; Cancer research; Stem cell; Apoptosis; Cancer cell; Cancer; Colorectal cancer; Programmed cell death; Biology; Medicine; Cell biology; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001115489,0.0001260454,0.0002073387,0.0003448718,0.0001960026,0.0004366271,0.0001282971,0.0003155217,0.004231664],"category_scores_gemma":[0.0002346805,0.0001652484,0.0001297353,0.0002424172,0.0002321869,0.0003270376,0.0002153883,0.0005447764,0.0005083631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003294849,"about_ca_system_score_gemma":0.0001835762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000298823,"about_ca_topic_score_gemma":0.0003661268,"domain_scores_codex":[0.9998862,0.00002075341,0.000009735148,0.00002476714,0.00002235364,0.00003608178],"domain_scores_gemma":[0.9997529,0.00004576197,0.00006958119,0.0000337061,0.00002547309,0.0000725214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004123234,0.00003356855,0.001661693,0.00002462252,0.000005399929,0.00006904616,0.00002387656,0.00007079404,0.9957566,0.0004160674,0.00008931335,0.001436764],"study_design_scores_gemma":[0.00004703782,0.0005515869,0.02596607,0.000007346419,0.00002162623,0.0007083826,0.0001231703,0.0009810637,0.9690587,0.000350393,0.002178095,0.000006523269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978574,0.0004616397,0.0005793836,0.0001268504,0.00001334605,0.000007425688,0.0001911999,0.00005032143,0.0007124495],"genre_scores_gemma":[0.9990339,0.0001093879,0.000158375,0.00002211748,0.000003398825,0.000006448115,0.0001360616,0.000008718801,0.0005215517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004231664,"threshold_uncertainty_score":0.01415634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01614578635286446,"score_gpt":0.2448555145693719,"score_spread":0.2287097282165075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}