{"id":"W2049243347","doi":"10.4161/rna.20807","title":"The imprinted H19 gene regulates human placental trophoblast cell proliferation via encoding miR-675 that targets Nodal Modulator 1 (NOMO1)","year":2012,"lang":"en","type":"article","venue":"RNA Biology","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":177,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Biology; Genomic imprinting; microRNA; Trophoblast; Cell biology; Gene; Nodal signaling; NODAL; Cell growth; Genetics; Computational biology; Cancer research; Molecular biology; Embryonic stem cell; Placenta; Gene expression; DNA methylation; Gastrulation; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002623503,0.0002138789,0.0002978239,0.00005394349,0.0004799124,0.00001469016,0.0001275676,0.0001811946,0.00006529072],"category_scores_gemma":[0.00003921694,0.0001384758,0.0001046806,0.00006929093,0.0001813237,0.00009151649,0.0001250976,0.0002281302,0.00005584611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008320702,"about_ca_system_score_gemma":0.00002470342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003268825,"about_ca_topic_score_gemma":0.00002572956,"domain_scores_codex":[0.9987171,0.00012587,0.0002630495,0.0002563124,0.0001002189,0.0005374342],"domain_scores_gemma":[0.9993145,0.00009726366,0.0001324061,0.0002905361,0.00005006415,0.0001152351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001971448,0.000102241,0.1172131,0.00003151635,0.0001003925,0.000003081143,0.0007356022,0.000001188607,0.8799577,0.0003365725,0.0003285026,0.0009929517],"study_design_scores_gemma":[0.001481875,0.000383694,0.1149188,0.00004889959,0.00007724104,0.00008309942,0.0001554478,0.0003444633,0.877784,0.0003547528,0.004136248,0.0002314876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892485,0.006627355,0.0004881028,0.0004720555,0.0006598466,0.0004992274,0.00001359852,0.00008202304,0.001909336],"genre_scores_gemma":[0.9979642,0.0002152586,0.0003460375,0.0001555958,0.0005660656,0.00005773691,0.00008251987,0.00002140236,0.0005911821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008715747,"threshold_uncertainty_score":0.5646881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02003624076017112,"score_gpt":0.2643888893253166,"score_spread":0.2443526485651454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}