{"id":"W2049288252","doi":"10.1002/biof.36","title":"C/EBPα in leukemogenesis: Identity and origin of the leukemia‐initiating cell","year":2009,"lang":"en","type":"review","venue":"BioFactors","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"CEBPA; Myeloid leukemia; RUNX1; Myelopoiesis; Biology; Epigenetics; Transcription factor; Leukemia; Cancer research; Myeloid; Ccaat-enhancer-binding proteins; Genetics; Population; Gene; Medicine; DNA-binding protein; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003619116,0.000711405,0.001185164,0.001492954,0.0002720872,0.000716473,0.0007886892,0.0009488449,0.0021988],"category_scores_gemma":[0.0002678677,0.0002250901,0.0002307341,0.001900718,0.0006500135,0.00134876,0.0004817742,0.001217563,0.002632764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006757202,"about_ca_system_score_gemma":0.0007609809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008285077,"about_ca_topic_score_gemma":0.00118291,"domain_scores_codex":[0.9999012,0.0000149175,0.00001460739,0.00002165314,0.00003749628,0.00001005078],"domain_scores_gemma":[0.9998779,0.00004732304,0.00002055449,0.000005226314,0.00003233028,0.00001670363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009274996,0.00006205821,0.0001891129,0.009852865,0.00004271536,0.0003051634,0.00009757839,0.0003801586,0.0080499,0.007760973,0.01661734,0.9565495],"study_design_scores_gemma":[0.00001568331,0.00009085755,0.0009426028,0.002007852,0.00004682806,0.001782555,0.0001285931,0.00008183276,0.00160556,0.004002915,0.9892771,0.00001767236],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001691121,0.9983578,0.0001761713,0.000154352,0.000132166,0.000002501736,0.000008089307,0.000004288258,0.0009954959],"genre_scores_gemma":[0.0006917053,0.9982463,0.0001976092,0.00008126828,0.00008875554,0.000004016215,0.00001457223,9.149655e-7,0.0006747952],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0021988,"threshold_uncertainty_score":0.00735569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09669181009230585,"score_gpt":0.3774299391145445,"score_spread":0.2807381290222387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}