{"id":"W2049288252","doi":"10.1002/biof.36","title":"C/EBPα in leukemogenesis: Identity and origin of the leukemia‐initiating cell","year":2009,"lang":"en","type":"review","venue":"BioFactors","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"","keywords":"CEBPA; Myeloid leukemia; RUNX1; Myelopoiesis; Biology; Epigenetics; Transcription factor; Leukemia; Cancer research; Myeloid; Ccaat-enhancer-binding proteins; Genetics; Population; Gene; Medicine; DNA-binding protein; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006274758,0.0004635846,0.001816006,0.0004523206,0.00007115803,0.00003467131,0.0004889265,0.00057075,0.00006208788],"category_scores_gemma":[0.0003388771,0.0002926169,0.0004716605,0.001067203,0.0001832853,0.0001332315,0.0002726791,0.001029693,0.00002894669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001911846,"about_ca_system_score_gemma":0.003058388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00063609,"about_ca_topic_score_gemma":0.00006277352,"domain_scores_codex":[0.9971974,0.0002901091,0.0009043647,0.0005190258,0.0006057568,0.0004832936],"domain_scores_gemma":[0.9982551,0.0002755926,0.0004799979,0.000735843,0.00008016068,0.0001733411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002989774,0.0001360328,0.00736272,0.0417759,0.000186554,0.0001333681,0.000229927,9.508789e-7,0.0001482756,0.0001635614,0.0006986923,0.9491341],"study_design_scores_gemma":[0.001675244,0.0001884471,0.009541234,0.02290415,0.001207156,0.0001601592,0.0001401404,0.00002069274,0.0004792955,0.00005985773,0.9629563,0.0006673242],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02562673,0.9706032,0.000003347523,0.00002665724,0.0001744692,0.001259246,0.0000525998,0.00003174846,0.002222007],"genre_scores_gemma":[0.006130527,0.9926875,0.0001312907,0.00005892924,0.0001769508,0.00002814341,0.00003326107,0.00006645846,0.0006869147],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9622576,"threshold_uncertainty_score":0.9999526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09669181009230585,"score_gpt":0.3774299391145445,"score_spread":0.2807381290222387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}