{"id":"W2049317208","doi":"10.1038/nchem.1879","title":"Flexibility leads to function","year":2014,"lang":"en","type":"letter","venue":"Nature Chemistry","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Flexibility (engineering); Function (biology); Mass spectrometry; Enzyme; ATP synthase; Nanotechnology; Biophysics; Biochemical engineering; Biochemistry; Cell biology; Chromatography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001798027,0.0006329387,0.0005523128,0.0002594826,0.001767325,0.002434777,0.0008708104,0.005868156,0.005527052],"category_scores_gemma":[0.004832177,0.0002961298,0.0003339979,0.0001844753,0.00733617,0.003363227,0.002478616,0.009317206,0.002609295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001692327,"about_ca_system_score_gemma":0.0005892105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003353757,"about_ca_topic_score_gemma":0.0003538246,"domain_scores_codex":[0.9993475,0.0001131537,0.00002983339,0.0001415025,0.0002505731,0.00011754],"domain_scores_gemma":[0.9986272,0.0005681069,0.00007593098,0.0002991546,0.0001311967,0.0002984681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003181407,0.00005768516,0.0004922452,0.0001339565,0.00004718878,0.001831757,0.0003341784,0.0008642293,0.01024447,0.7043532,0.2310861,0.05023687],"study_design_scores_gemma":[0.000100178,0.00007084185,0.0004152821,0.00004025126,0.000018022,0.0009396311,0.0001525538,0.001700512,0.004699224,0.6919237,0.299898,0.00004171813],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0241809,0.01526104,0.01651967,0.8022271,0.03906678,0.00002867152,0.0001549897,0.0005671567,0.1019936],"genre_scores_gemma":[0.6333218,0.01029483,0.004941882,0.2660931,0.02022498,0.0001497274,0.0001487128,0.0002888685,0.06453606],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.005868156,"threshold_uncertainty_score":0.01848984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01330114112028708,"score_gpt":0.3026430347338829,"score_spread":0.2893418936135958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}