{"id":"W2049361389","doi":"10.1592/phco.23.1.29.31915","title":"Tenofovir: A Nucleotide Analog for The Management of Human Immunodeficiency Virus Infection","year":2003,"lang":"en","type":"review","venue":"Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; St. Michael's Hospital; Toronto Public Health","funders":"","keywords":"Efavirenz; Stavudine; Zidovudine; Lamivudine; Pharmacology; Virology; Adverse effect; Medicine; Reverse-transcriptase inhibitor; Hypophosphatemia; Internal medicine; Gastroenterology; Viral load; Virus; Viral disease; Antiretroviral therapy; Hepatitis B virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001855289,0.0003076152,0.0002278505,0.0004382496,0.0001891896,0.0002440135,0.0002495573,0.0004585172,0.003850364],"category_scores_gemma":[0.0001902798,0.00004158599,0.0001609411,0.0002354566,0.0001275765,0.0001806675,0.0002083631,0.000589288,0.001148836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001851037,"about_ca_system_score_gemma":0.0001635618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002823015,"about_ca_topic_score_gemma":0.0005970747,"domain_scores_codex":[0.9999331,0.00001609907,0.000005999924,0.000007127008,0.00002536529,0.00001233657],"domain_scores_gemma":[0.9999518,0.000006014254,0.00001201221,0.000002116783,0.000006294745,0.00002168724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001088321,0.0004290595,0.0009437248,0.001154593,0.00005082049,0.001322348,0.00005825881,0.0002740831,0.05022234,0.00158,0.02727133,0.9156051],"study_design_scores_gemma":[0.001758794,0.003761065,0.009950846,0.0008102693,0.000119021,0.02236052,0.00006276035,0.0009114013,0.03200492,0.001996859,0.9262123,0.00005137385],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1292683,0.7909455,0.01210187,0.006931128,0.003201119,0.0006539809,0.000906426,0.0009888632,0.05500275],"genre_scores_gemma":[0.6225278,0.319611,0.019632,0.003710974,0.002140171,0.0004569234,0.001536522,0.00009069134,0.03029404],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003850364,"threshold_uncertainty_score":0.0128808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05300262064673796,"score_gpt":0.4021831293945341,"score_spread":0.3491805087477962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}