{"id":"W2049401934","doi":"10.1371/journal.pgen.1003396","title":"Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; Azrieli Foundation","keywords":"Biology; Gene; Genetics; Genotype; Genetic variation; Computational biology; Set (abstract data type); Variation (astronomy); Expression (computer science); Gene expression; Evolutionary biology; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005460316,0.0001238538,0.0001224096,0.00005372021,0.00008814799,0.00004308081,0.0001733392,0.0001639112,0.00004542907],"category_scores_gemma":[0.00001800731,0.0001174758,0.00004292149,0.00004281715,0.00006524068,0.000013594,0.0001292969,0.0000587607,0.000005429652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001212055,"about_ca_system_score_gemma":0.00004261074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001591606,"about_ca_topic_score_gemma":0.000009107527,"domain_scores_codex":[0.9991895,0.00002891189,0.0003255873,0.000137873,0.0001626032,0.0001555209],"domain_scores_gemma":[0.9993165,0.000004311786,0.0002159035,0.000257975,0.000148853,0.00005650771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000001866307,0.00004402705,0.2084312,0.00003868664,0.00003044855,3.686358e-8,0.0001631373,0.003633511,0.7873455,0.000009001016,0.0001040854,0.0001984922],"study_design_scores_gemma":[0.0004536472,0.0003466582,0.3381289,0.00006523274,0.00006301989,0.000004440083,0.0002779902,0.06353062,0.5963443,0.0004063071,0.0001175058,0.0002614211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977826,0.00009096136,0.001456807,0.000004810617,0.00005949783,0.0002514748,0.00006178446,0.000009679629,0.0002823672],"genre_scores_gemma":[0.9943616,0.0000552744,0.005164854,0.00002062727,0.00006544289,0.000007418322,0.0002804631,0.00001398414,0.00003038417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1910012,"threshold_uncertainty_score":0.4790526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02201886509714594,"score_gpt":0.2091888882000506,"score_spread":0.1871700231029047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}