{"id":"W2049419155","doi":"10.1155/2015/430569","title":"Mechanical Stress Promotes Cisplatin-Induced Hepatocellular Carcinoma Cell Death","year":2015,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; American University in Cairo","keywords":"Cisplatin; Programmed cell death; Oxidative stress; Hepatocellular carcinoma; Carnosine; Pharmacology; Cancer research; Chemistry; Apoptosis; Medicine; Biochemistry; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002033726,0.0001858753,0.0001519828,0.0003667731,0.0001387588,0.0001304429,0.001029425,0.0002826159,0.0001572793],"category_scores_gemma":[0.001174015,0.0001702923,0.00009407892,0.0003038014,0.0001283961,0.00001303672,0.0009212026,0.0004602032,0.0002354819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001981236,"about_ca_system_score_gemma":0.0007909153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002971449,"about_ca_topic_score_gemma":0.00002328235,"domain_scores_codex":[0.9960454,0.0004511066,0.0003034886,0.0006456558,0.001822441,0.0007318807],"domain_scores_gemma":[0.9975054,0.00005360223,0.0000455167,0.0005554205,0.001249955,0.0005901023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002173517,0.0002990173,0.01270051,0.00002382958,0.00004942544,0.00009603694,0.00004931512,0.000001918182,0.9795308,0.0003953865,0.005403763,0.001232652],"study_design_scores_gemma":[0.001127539,0.0007491311,0.0008973817,0.00001738816,0.000002489268,0.00002358501,0.0001176923,0.004012046,0.9603095,0.0003651872,0.03218137,0.0001966684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896531,0.0001596227,0.0007152406,0.001084459,0.0004582471,0.0006536818,0.0000935523,0.00002319744,0.00715896],"genre_scores_gemma":[0.9929992,0.00002175002,0.001485488,0.00003011653,0.001043336,0.0001821599,0.0004392214,0.0000437582,0.003754965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02677761,"threshold_uncertainty_score":0.6944317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1246177118066463,"score_gpt":0.3822558532566274,"score_spread":0.2576381414499812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}