{"id":"W2049479971","doi":"10.1016/s0014-5793(02)02394-3","title":"A rapid fluorometric assay for the proteolytic activity of SKI‐1/S1P based on the surface glycoprotein of the hemorrhagic fever Lassa virus","year":2002,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Ottawa Hospital; University of Ottawa","funders":"Medical Research Council; Ottawa Hospital Research Institute; University of Ottawa","keywords":"Lassa virus; Glycoprotein; Chemistry; Protease; Molecular biology; Virus; Virology; Biochemistry; Cleavage (geology); Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008848417,0.0001652954,0.0002731461,0.0001427614,0.0002282861,0.00002557619,0.0002828424,0.00007572366,0.0006729005],"category_scores_gemma":[0.0006942497,0.00007401036,0.0003073125,0.001189306,0.0002589606,0.00005172394,0.00005856748,0.0004310909,0.00002758843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001061119,"about_ca_system_score_gemma":0.00004938232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003630146,"about_ca_topic_score_gemma":0.00001507081,"domain_scores_codex":[0.9983504,0.0002872704,0.0002239338,0.000219668,0.0006038854,0.0003148391],"domain_scores_gemma":[0.9977446,0.001206025,0.0001592668,0.0007276913,0.0001119206,0.0000504517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005208904,0.0007016521,0.002200333,0.0003084824,0.0001916554,0.000006931796,0.0001686517,0.0008592628,0.9424175,0.00005354161,0.02002183,0.03254928],"study_design_scores_gemma":[0.002745211,0.000837393,0.03916032,0.0001949471,0.0001531565,0.00001730475,0.00004348385,0.09487271,0.8528954,0.00001407112,0.00886218,0.0002038077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9408008,0.0001485667,0.0020486,0.05308011,0.0001359169,0.00308432,0.00004632308,0.00002213979,0.0006332318],"genre_scores_gemma":[0.995819,0.00001214892,0.0001851111,0.002769997,0.00008385035,0.0001640112,0.000001121476,0.00002523906,0.0009395095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09401345,"threshold_uncertainty_score":0.7367788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04326361050301517,"score_gpt":0.2712948161184123,"score_spread":0.2280312056153971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}