{"id":"W2049579004","doi":"10.3851/imp1443","title":"Factors Affecting Template Usage in the Development of K65R Resistance in Subtype C Variants of HIV Type-1","year":2009,"lang":"en","type":"article","venue":"Antiviral chemistry & chemotherapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Reverse transcriptase; Template; DNA; Nucleotide; Molecular biology; Genetics; RNA; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000316111,0.0001422642,0.0002590981,0.00004032364,0.0000435114,0.000004561638,0.000221278,0.0001212526,0.0001101529],"category_scores_gemma":[0.00004897212,0.00009912386,0.0000451889,0.0002642044,0.00007976773,0.00004193354,0.00001306551,0.0001980736,0.00001254235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004021706,"about_ca_system_score_gemma":0.00009444854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001775185,"about_ca_topic_score_gemma":0.00006394631,"domain_scores_codex":[0.9991038,0.00007294655,0.0002959537,0.0001912471,0.00005950307,0.000276496],"domain_scores_gemma":[0.9995045,0.0001422363,0.0001127802,0.000204722,0.00002674041,0.000008989809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003150459,0.0003459606,0.06215488,0.0000494685,0.00005162425,0.00001052353,0.003318802,2.941777e-7,0.9314744,0.000006265407,0.0001405134,0.002132153],"study_design_scores_gemma":[0.0009530752,0.00004190254,0.2972745,0.00007181548,0.000002324277,0.000001373278,0.0002878859,1.417633e-7,0.7008229,0.00002702909,0.0004477508,0.00006924116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949273,0.0005674845,0.000005060017,0.00009223667,0.000016757,0.0001377858,0.00001195163,0.000007989103,0.004233416],"genre_scores_gemma":[0.9990469,0.00005832129,0.0001221518,0.00001957603,0.0000055541,0.000002286202,0.00006417164,0.000006759145,0.0006742458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2351196,"threshold_uncertainty_score":0.4042154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02272376542692057,"score_gpt":0.2800671230437076,"score_spread":0.257343357616787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}