{"id":"W2049589423","doi":"10.1007/s12609-013-0121-0","title":"Novel Therapies for Metastatic HER2 Positive Breast Cancer","year":2013,"lang":"en","type":"article","venue":"Current Breast Cancer Reports","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Pertuzumab; Trastuzumab; Medicine; Lapatinib; Metastatic breast cancer; Docetaxel; Oncology; Trastuzumab emtansine; Internal medicine; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003254529,0.0004174419,0.0006283562,0.0005512964,0.0002446607,0.0006350884,0.0005187997,0.0004747253,0.00911819],"category_scores_gemma":[0.0002127875,0.0001285834,0.0005129781,0.0003584973,0.0002822089,0.0007980281,0.0003861497,0.001264613,0.001493605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000433398,"about_ca_system_score_gemma":0.0002560582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002583303,"about_ca_topic_score_gemma":0.001639168,"domain_scores_codex":[0.9999137,0.00001884555,0.000005880624,0.00001364919,0.00002317787,0.00002480872],"domain_scores_gemma":[0.9999343,0.00002125793,0.0000155145,0.000005242168,0.00001035017,0.00001328753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001290625,0.001139379,0.0008304692,0.002113536,0.0001583354,0.0008176715,0.0001452943,0.0006926113,0.06063717,0.006656492,0.02074381,0.9047745],"study_design_scores_gemma":[0.003374144,0.009875502,0.008939257,0.001411472,0.0007388259,0.006530257,0.0003370859,0.001882813,0.0500769,0.008979895,0.9077885,0.00006538017],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.101898,0.8318316,0.004890043,0.009965878,0.002695958,0.0002685702,0.0005696481,0.0002652249,0.04761514],"genre_scores_gemma":[0.3563537,0.5849596,0.006494881,0.004817078,0.002359536,0.0003793646,0.00117821,0.00006518112,0.04339257],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00911819,"threshold_uncertainty_score":0.03050339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06508384817084498,"score_gpt":0.4015346760583286,"score_spread":0.3364508278874836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}