{"id":"W2049638724","doi":"10.1016/j.jot.2014.06.001","title":"A novel in vitro system for intracellular delivery of nonviral DNA","year":2014,"lang":"en","type":"article","venue":"Journal of Orthopaedic Translation","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Shanghai Jiao Tong University; Science and Technology Commission of Shanghai Municipality; Chinese Academy of Sciences; Shanghai Municipal Education Commission; National Natural Science Foundation of China","keywords":"Transfection; Intracellular; Cell biology; Chondrocyte; Cell; Cancer cell; Exogenous DNA; Gene delivery; Plasmid; Liposome; DNA; Molecular biology; Biology; Chemistry; In vitro; Cell culture; Cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004798181,0.00008145779,0.0001822263,0.0001073465,0.00001536937,0.000006055984,0.00009945257,0.0001041895,0.000001784862],"category_scores_gemma":[0.00002626113,0.00007336887,0.0001880344,0.00005729231,0.0000244184,0.00001103049,0.00000557263,0.00007033347,4.550429e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001083627,"about_ca_system_score_gemma":0.00005716871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000650216,"about_ca_topic_score_gemma":0.00001392121,"domain_scores_codex":[0.9991553,0.00003579339,0.0004784741,0.00009799983,0.0001259749,0.000106486],"domain_scores_gemma":[0.9994252,0.00002336991,0.0002683488,0.00009080745,0.0001553901,0.00003689317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008353788,0.00005118761,0.0007584318,0.0000749946,0.00003142817,0.000001184066,0.00007093942,0.0003581798,0.9730111,0.00001273991,0.00002313854,0.02477126],"study_design_scores_gemma":[0.00259471,0.0008049449,0.001890655,0.000117774,0.00005381729,0.00004662931,0.000106779,0.002947116,0.9887831,0.00001599103,0.002532641,0.0001057945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8648589,0.000608419,0.1340956,0.00005306244,0.0001935246,0.00009589051,0.00001121676,0.000001502381,0.00008182849],"genre_scores_gemma":[0.995623,0.00005207181,0.003981372,0.00002381793,0.0002702174,0.000002850187,0.00002328503,0.000009370067,0.0000140028],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1307641,"threshold_uncertainty_score":0.2991896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0133160538313583,"score_gpt":0.2287453378174971,"score_spread":0.2154292839861388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}