{"id":"W2049695886","doi":"10.1016/j.cub.2011.01.025","title":"Split Introns in the Genome of Giardia intestinalis Are Excised by Spliceosome-Mediated trans-Splicing","year":2011,"lang":"en","type":"article","venue":"Current Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Spliceosome; Biology; Intron; RNA splicing; Genetics; Giardia lamblia; Trans-splicing; Gene; Genome; Eukaryote; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002602155,0.0003226915,0.0003706828,0.0003222371,0.0002383001,0.0005671962,0.0002024199,0.0006175752,0.000700357],"category_scores_gemma":[0.0003088724,0.0002784549,0.000463345,0.0001986693,0.0004199204,0.0002610086,0.0004088618,0.000889492,0.0009737567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002624865,"about_ca_system_score_gemma":0.0002421843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000394865,"about_ca_topic_score_gemma":0.0008067614,"domain_scores_codex":[0.9998083,0.00002854838,0.000008870466,0.00006136783,0.0000633173,0.00002972012],"domain_scores_gemma":[0.9997172,0.00006234425,0.00007084844,0.00004961642,0.00004696289,0.00005314097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001101348,0.00001060173,0.001247216,0.00004759775,0.000009714428,0.0001603619,0.0000725155,0.0000880588,0.9933271,0.0003579389,0.0000693091,0.004499442],"study_design_scores_gemma":[0.00004357355,0.0002695354,0.047116,0.00003577071,0.00007712677,0.001559506,0.0002677541,0.002144691,0.9414933,0.001152245,0.005819368,0.00002122018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875431,0.002076941,0.008067862,0.0001726685,0.0000536477,0.00001145269,0.0001716307,0.000186104,0.001716544],"genre_scores_gemma":[0.9922511,0.0004549561,0.004655357,0.00008926159,0.00002095658,0.000009171059,0.0009175744,0.00007047737,0.001531265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000700357,"threshold_uncertainty_score":0.002342939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03836131214456083,"score_gpt":0.2923557948417594,"score_spread":0.2539944826971986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}