{"id":"W2049695886","doi":"10.1016/j.cub.2011.01.025","title":"Split Introns in the Genome of Giardia intestinalis Are Excised by Spliceosome-Mediated trans-Splicing","year":2011,"lang":"en","type":"article","venue":"Current Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Spliceosome; Biology; Intron; RNA splicing; Genetics; Giardia lamblia; Trans-splicing; Gene; Genome; Eukaryote; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004233861,0.0001709474,0.0002471691,0.00009052342,0.00004642742,0.000006954197,0.0004959739,0.0001393646,0.00004934187],"category_scores_gemma":[0.0001926986,0.0001239177,0.0001007038,0.0001982967,0.0002326917,0.000003893865,0.00008767214,0.000252489,0.00001095723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001444615,"about_ca_system_score_gemma":0.00005001533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001666713,"about_ca_topic_score_gemma":0.00009456552,"domain_scores_codex":[0.9985806,0.0002281985,0.0003261113,0.0003475317,0.00008890724,0.000428691],"domain_scores_gemma":[0.9992798,0.00005842833,0.000123538,0.0003836083,0.00007092363,0.00008369149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001272822,0.0001684371,0.05206548,0.00004220731,0.00002878147,0.000002598206,0.0003083184,0.000001179852,0.9426678,0.000173649,0.0006240762,0.003790172],"study_design_scores_gemma":[0.007309952,0.004125135,0.5806909,0.0003329882,0.0001378864,0.00009813049,0.003116892,0.0004847145,0.2282257,0.001225663,0.1723901,0.001861853],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936472,0.003928781,0.00133213,0.0001545605,0.0001003591,0.00029832,0.0001191339,0.000008544894,0.0004109792],"genre_scores_gemma":[0.9984505,0.0007541337,0.00009504778,0.00009751085,0.00009640628,0.0000566581,0.0003911169,0.00001414678,0.00004450297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7144421,"threshold_uncertainty_score":0.5053216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03836131214456083,"score_gpt":0.2923557948417594,"score_spread":0.2539944826971986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}