{"id":"W2049700201","doi":"10.1016/j.intimp.2009.01.023","title":"Prostaglandin E2 signaling through E prostanoid receptor 2 impairs proliferative response of double negative regulatory T cells","year":2009,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Prostaglandin E2 receptor; Prostanoid; Cell biology; CD8; Biology; Receptor; Prostaglandin D2; T cell; Agonist; Prostaglandin E2; Prostaglandin; Immunology; Immune system; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003579523,0.0006595656,0.0005513582,0.000408485,0.0002417559,0.00050289,0.0004276591,0.0006651363,0.003508221],"category_scores_gemma":[0.0002548686,0.0003328498,0.0003500703,0.0002074325,0.0004228445,0.0003506535,0.0002207648,0.002018518,0.0006557347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002409836,"about_ca_system_score_gemma":0.0002821933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002712914,"about_ca_topic_score_gemma":0.0004000205,"domain_scores_codex":[0.9992844,0.0001641378,0.00005391438,0.0001081323,0.0001303288,0.0002590384],"domain_scores_gemma":[0.9997342,0.00006645149,0.0000487428,0.00004123439,0.00001557866,0.00009377438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007208642,0.0001665964,0.0001060431,0.00002148417,0.000004184568,0.00008057221,0.00001310881,0.00005069631,0.9980608,0.0001024024,0.00006207391,0.0006112463],"study_design_scores_gemma":[0.0002962483,0.001559434,0.003697225,0.00000704147,0.00003172691,0.000338221,0.00008298823,0.001381757,0.9907445,0.0001414788,0.001710231,0.000009217942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977005,0.000251562,0.0005801966,0.00007072298,0.00008294133,0.00002068728,0.0001310375,0.00005393257,0.00110849],"genre_scores_gemma":[0.9956484,0.0002040521,0.00065437,0.0001112828,0.00004269914,0.000067619,0.0002417173,0.00002289142,0.003006963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003508221,"threshold_uncertainty_score":0.01173615,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01443686249687224,"score_gpt":0.2880441663452981,"score_spread":0.2736073038484258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}