{"id":"W2049724639","doi":"10.1615/critrevtherdrugcarriersyst.v19.i45.20","title":"Current Status of DNA Vaccines and Their Route of Administration;","year":2002,"lang":"en","type":"review","venue":"Critical Reviews in Therapeutic Drug Carrier Systems","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"DNA vaccination; Vaccination; Medicine; Delivery system; Immunology; Risk analysis (engineering); Immunization; Immune system; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008918445,0.001075192,0.001248686,0.001812513,0.0003815765,0.001497875,0.001140624,0.001685442,0.005176937],"category_scores_gemma":[0.0008941206,0.0003723161,0.0003732236,0.001592467,0.000782929,0.00232625,0.000608007,0.001794361,0.007479632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000834161,"about_ca_system_score_gemma":0.001374528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009246665,"about_ca_topic_score_gemma":0.0009339391,"domain_scores_codex":[0.9995977,0.0001001865,0.00003785597,0.00007442504,0.0001652538,0.00002449928],"domain_scores_gemma":[0.9996778,0.0001449515,0.00006685498,0.0000165789,0.00006566207,0.00002817253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001003746,0.00008538577,0.0001576445,0.00946407,0.0000295876,0.0002827005,0.00009017159,0.0004174449,0.01386732,0.0074818,0.0115711,0.9564524],"study_design_scores_gemma":[0.0000134416,0.0001197454,0.0002450349,0.001048779,0.00004117339,0.00172679,0.0000503379,0.00009264438,0.00437792,0.002047,0.9902205,0.00001662353],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003491311,0.9927711,0.002492927,0.000326811,0.0003574774,0.00001974269,0.00002938994,0.00003800219,0.003615399],"genre_scores_gemma":[0.001967009,0.9910466,0.002848797,0.0002856987,0.0002575715,0.0000607556,0.00007190658,0.00001154743,0.003450153],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005176937,"threshold_uncertainty_score":0.01731855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06683106645513742,"score_gpt":0.3706867754032659,"score_spread":0.3038557089481285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}