{"id":"W2049724639","doi":"10.1615/critrevtherdrugcarriersyst.v19.i45.20","title":"Current Status of DNA Vaccines and Their Route of Administration;","year":2002,"lang":"en","type":"review","venue":"Critical Reviews in Therapeutic Drug Carrier Systems","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Drug Research and Development","funders":"","keywords":"DNA vaccination; Vaccination; Medicine; Delivery system; Immunology; Risk analysis (engineering); Immunization; Immune system; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005016421,0.0004256537,0.002006953,0.0001024333,0.00002238444,0.0000258068,0.0003091705,0.0002381475,0.00001785259],"category_scores_gemma":[0.0002586344,0.0002918397,0.0004287792,0.0001637456,0.0001614582,0.000006585899,0.00008901415,0.0002035285,0.000004169775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003399441,"about_ca_system_score_gemma":0.0002385185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000184747,"about_ca_topic_score_gemma":0.00001466506,"domain_scores_codex":[0.996948,0.000610411,0.001490872,0.0004707137,0.0001303137,0.0003497098],"domain_scores_gemma":[0.998588,0.0001384752,0.000373469,0.0006106747,0.0001487234,0.0001407172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001071742,0.00009274449,0.00009249935,0.03660537,0.0001194732,0.000001549405,0.000100304,1.622904e-7,0.0001655343,0.0008862347,0.0002386146,0.9616868],"study_design_scores_gemma":[0.0001155694,0.0001516463,0.000006025101,0.01552685,0.000235757,0.0000271222,0.00009389773,0.000008005845,0.0001522469,0.00003859361,0.9833807,0.0002635299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003234009,0.9974948,0.0001607208,0.000007204756,0.0006386824,0.0008701332,0.0002767611,0.000003328285,0.0002249292],"genre_scores_gemma":[0.03138494,0.9680193,0.000008770833,0.00001343323,0.0001754006,0.0001655372,0.00007828909,0.00003130975,0.0001229943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9831421,"threshold_uncertainty_score":0.9999534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06683106645513742,"score_gpt":0.3706867754032659,"score_spread":0.3038557089481285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}