{"id":"W2049730817","doi":"10.1016/j.humimm.2009.12.007","title":"A census of predicted mutational epitopes suitable for immunologic cancer control","year":2010,"lang":"en","type":"article","venue":"Human Immunology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Genome British Columbia; Genome Canada","keywords":"Epitope; Human leukocyte antigen; Biology; KRAS; Antigen; Immunology; Immune system; Gene; Genetics; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001653728,0.0001495258,0.0002386216,0.00006051946,0.0001408853,0.00001330607,0.0002817599,0.0002718304,0.0000968302],"category_scores_gemma":[0.0001192407,0.0001333464,0.0001127855,0.00005161811,0.0001703168,0.000006914821,0.00007629843,0.0001634599,0.000002065657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007483947,"about_ca_system_score_gemma":0.00007494286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006571755,"about_ca_topic_score_gemma":0.00005599849,"domain_scores_codex":[0.9990788,0.00002786908,0.000364436,0.0001866534,0.00005662747,0.0002855923],"domain_scores_gemma":[0.9991729,0.00003330816,0.0002134295,0.0003265646,0.0002323058,0.00002146612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001884818,0.00008705064,0.001407443,0.00002873586,0.0002900652,2.455272e-7,0.00007293532,0.00004031327,0.9925771,0.003410441,0.000651264,0.001245976],"study_design_scores_gemma":[0.01366432,0.003036815,0.173959,0.00003829642,0.0001985906,0.0001184831,0.0007471143,0.001162429,0.6966472,0.00274118,0.106804,0.000882572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964594,0.001445207,0.000516079,0.000107545,0.0003559269,0.0003916894,0.0003113044,0.00001659471,0.0003962335],"genre_scores_gemma":[0.9976931,0.00008039212,0.0007936495,0.00007445415,0.0001295149,0.0002279776,0.0005127381,0.00001916395,0.0004689987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2959298,"threshold_uncertainty_score":0.5437707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294606091896971,"score_gpt":0.266055072953324,"score_spread":0.2531090120343543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}