{"id":"W2049766622","doi":"10.1182/blood-2014-07-587600","title":"FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Platelet; FLNA; Cell biology; Megakaryocyte; Biology; Chemistry; Cytoskeleton; Filamin; Cell; Immunology; Biochemistry; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008450572,0.0002315552,0.0002008348,0.0001525685,0.0001752497,0.0003425068,0.000139883,0.0003415361,0.00137988],"category_scores_gemma":[0.0001187183,0.0002116235,0.0002206169,0.00008182813,0.0001705581,0.0002214436,0.000287447,0.0004343427,0.000488156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003335464,"about_ca_system_score_gemma":0.000122907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005633064,"about_ca_topic_score_gemma":0.0007969373,"domain_scores_codex":[0.999882,0.00002035954,0.00001148885,0.00002616719,0.00002409706,0.00003590092],"domain_scores_gemma":[0.9998977,0.00001241602,0.00002572695,0.000007089899,0.000009223456,0.00004789793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005235335,0.000004632094,0.0001599492,0.0000112541,0.000001664127,0.00006406616,0.000009129022,0.00001486058,0.9994602,0.00006452266,0.00002188039,0.0001356073],"study_design_scores_gemma":[0.0000364372,0.0001453093,0.06578067,0.00001158343,0.00001949961,0.0007251633,0.0001054501,0.00241222,0.927357,0.0000928834,0.003304085,0.000009673966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971668,0.0007803582,0.0008666529,0.00005636082,0.00001076222,0.000008436175,0.0001696776,0.00003175443,0.0009091414],"genre_scores_gemma":[0.9958942,0.0003095304,0.0006320488,0.00004774488,0.000006756261,0.00002918055,0.0003587104,0.0000160875,0.00270576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00137988,"threshold_uncertainty_score":0.004616141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782659519966891,"score_gpt":0.2536879364962414,"score_spread":0.2358613412965725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}