{"id":"W2049852944","doi":"10.1515/hc.2008.14.5.385","title":"2-(3-ARYLACRYLOYL)-3-METHYLQUINOXALINE 1,4-DIOXIDES AS POTENTIAL HYPOXIC SELECTIVE CYTOTOXINS","year":2008,"lang":"en","type":"article","venue":"Heterocyclic Communications","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cytotoxicity; Combinatorial chemistry; Pharmacology; Stereochemistry; Biochemistry; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001374745,0.0003314928,0.0001819808,0.000194621,0.0001385016,0.0001524824,0.0002030659,0.0002039224,0.0009937921],"category_scores_gemma":[0.0001003008,0.0001158673,0.0001159428,0.0001495933,0.0001697576,0.0002629669,0.0002161427,0.0002428857,0.0003007668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002242675,"about_ca_system_score_gemma":0.0001483491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002281636,"about_ca_topic_score_gemma":0.0007055014,"domain_scores_codex":[0.9999417,0.00001257045,0.000004507835,0.000009911362,0.00001670299,0.00001460118],"domain_scores_gemma":[0.9999466,0.000010813,0.00001657226,0.000003948537,0.000008260287,0.00001384567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001057759,0.00002457823,0.0001584329,0.00009359639,0.000003958612,0.000121354,0.00004192769,0.0003155034,0.9932406,0.0005644041,0.00008157793,0.005248464],"study_design_scores_gemma":[0.00004704697,0.0009538904,0.001217077,0.000009416108,0.0000148911,0.0002936412,0.00003348791,0.000540988,0.9885806,0.0001362757,0.008162049,0.00001060716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840928,0.006386884,0.004779622,0.0001499266,0.00004161636,0.00006867637,0.0001795975,0.00008111571,0.004219707],"genre_scores_gemma":[0.9886478,0.004308219,0.002854059,0.00005273652,0.00002268225,0.00006082964,0.0002875723,0.00001456182,0.003751535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009937921,"threshold_uncertainty_score":0.003324568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04316462557830602,"score_gpt":0.2756894825239549,"score_spread":0.2325248569456489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}