{"id":"W2049877674","doi":"10.1021/acs.bioconjchem.5b00139","title":"Lack of in Vivo Antibody Dependent Cellular Cytotoxicity with Antibody Containing Gold Nanoparticles","year":2015,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Antibody-dependent cell-mediated cytotoxicity; Cetuximab; Panitumumab; In vivo; Chemistry; Antibody; Cytotoxicity; Monoclonal antibody; Cancer research; In vitro; Immunology; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003984711,0.0003944699,0.0003739011,0.000150368,0.0001192539,0.0002548115,0.000223391,0.0005114287,0.0006159349],"category_scores_gemma":[0.0003472342,0.0002075969,0.0002362615,0.00009617805,0.0002930114,0.0002665544,0.00015559,0.0006147689,0.0002055459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003086275,"about_ca_system_score_gemma":0.0002018492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007788063,"about_ca_topic_score_gemma":0.001002015,"domain_scores_codex":[0.9996521,0.00007116447,0.00003406436,0.00009609635,0.00009229993,0.00005420375],"domain_scores_gemma":[0.9997154,0.0001003369,0.00006524954,0.00004731029,0.00004701779,0.00002453705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005843516,0.00002942853,0.00005180239,0.00003004644,0.000005598874,0.00002404132,0.00001440615,0.00006659791,0.9990546,0.00006235548,0.00002332424,0.0005792925],"study_design_scores_gemma":[0.000005363902,0.000238716,0.0002104627,0.000001582637,0.00000672135,0.00004976599,0.00000337636,0.0003512241,0.9987674,0.0000115307,0.0003526961,0.000001256488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866838,0.001280441,0.009610589,0.0001238391,0.00006276182,0.00007377631,0.0001230726,0.00009714291,0.001944554],"genre_scores_gemma":[0.9916504,0.000469014,0.004360713,0.00008513493,0.00001119743,0.00007024104,0.0002622588,0.00003574523,0.003055262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007788063,"threshold_uncertainty_score":0.002239287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0561089842736499,"score_gpt":0.339568696835137,"score_spread":0.2834597125614871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}