{"id":"W2049877674","doi":"10.1021/acs.bioconjchem.5b00139","title":"Lack of in Vivo Antibody Dependent Cellular Cytotoxicity with Antibody Containing Gold Nanoparticles","year":2015,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Antibody-dependent cell-mediated cytotoxicity; Cetuximab; Panitumumab; In vivo; Chemistry; Antibody; Cytotoxicity; Monoclonal antibody; Cancer research; In vitro; Immunology; Biochemistry; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003939297,0.0002338894,0.0005073559,0.00005811044,0.00002909974,0.00002025659,0.0001799139,0.0001378194,0.0001699999],"category_scores_gemma":[0.00008283839,0.0001798978,0.00007881013,0.0002416951,0.0002756982,0.00007267809,0.0001178116,0.0002768669,0.0000228811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008433346,"about_ca_system_score_gemma":0.0002936615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004571505,"about_ca_topic_score_gemma":0.00001686621,"domain_scores_codex":[0.9981226,0.00003678199,0.0004235847,0.0003737703,0.0005760951,0.0004671627],"domain_scores_gemma":[0.9989062,0.00005264448,0.0001260234,0.0003310013,0.000209027,0.0003751274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001444431,0.0002670822,0.1474618,0.0004081401,0.00005587627,0.0005532802,0.0001602938,0.000008367763,0.8494278,0.00004503231,0.0001210186,0.0000468535],"study_design_scores_gemma":[0.002613561,0.0004020057,0.004043832,0.0003148575,0.00003105612,0.0001391905,0.0005454983,0.0002032064,0.9902937,0.00004848843,0.001151915,0.0002126955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989876,0.0005827536,0.00001626706,0.0003059499,0.00002543008,0.0003005804,0.00004382596,0.00003435263,0.008814895],"genre_scores_gemma":[0.9970133,0.00007925479,0.0002666014,0.0001003748,0.0001153436,0.00001305579,0.00007174036,0.00002628046,0.00231409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.143418,"threshold_uncertainty_score":0.733602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0561089842736499,"score_gpt":0.339568696835137,"score_spread":0.2834597125614871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}