{"id":"W2049922114","doi":"10.1002/stem.589","title":"Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury","year":2010,"lang":"en","type":"article","venue":"Stem Cells","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Biology; Wnt signaling pathway; Neural stem cell; Stem cell; Subependymal zone; Cell biology; Neurosphere; Progenitor cell; Population; Adult stem cell; Neurogenesis; Asymmetric cell division; Cell division; Endothelial stem cell; Signal transduction; Cell; Neuroscience; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009349501,0.0001710753,0.0002846674,0.0002867644,0.0000466825,0.00003113057,0.0003761282,0.00007507137,0.000006480232],"category_scores_gemma":[0.0001402891,0.0001286661,0.00005350864,0.0005882464,0.00008089505,0.00008309775,0.0001644595,0.0002564049,0.000005932736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007352784,"about_ca_system_score_gemma":0.00002328522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001509119,"about_ca_topic_score_gemma":0.00001747169,"domain_scores_codex":[0.9976095,0.0008177794,0.0004880836,0.0004333378,0.0003799471,0.0002713745],"domain_scores_gemma":[0.9968794,0.002497065,0.0001684952,0.0003459537,0.00003552526,0.00007356593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005169681,0.00008975616,0.000276498,0.00005111069,5.963641e-7,0.0000341165,0.0005817969,0.0001333308,0.9971292,0.0002544357,0.00001783432,0.0009143667],"study_design_scores_gemma":[0.0003111289,0.0004231338,0.001694031,0.00007156988,0.000003703999,0.000006817143,0.0001858043,0.0006171398,0.996509,0.00003181014,0.00003160736,0.000114227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998943,0.000009026438,0.00001278948,0.000217188,0.0003381729,0.0004191553,0.0000333588,0.00001177512,0.00001557873],"genre_scores_gemma":[0.9992844,0.000007236458,0.00003390559,0.0005623504,0.00001271766,0.000007040913,8.678759e-8,0.0000217013,0.00007055244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001679286,"threshold_uncertainty_score":0.524685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0168942960420074,"score_gpt":0.2454366535856243,"score_spread":0.2285423575436169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}