{"id":"W2049925231","doi":"10.1038/mi.2013.128","title":"Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity","year":2014,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; GlaxoSmithKline","keywords":"ISG15; Innate immune system; Interferon-stimulated gene; Biology; Interferon; Rhinovirus; Immunology; CXCL10; Proinflammatory cytokine; Cell biology; Immunity; Immune system; Secretion; Chemokine; Gene; Virus; Inflammation; Ubiquitin; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001468579,0.0001599209,0.0001920113,0.0001274867,0.00007099962,0.000226029,0.00007817757,0.0001992507,0.0008341057],"category_scores_gemma":[0.0001065266,0.00005743769,0.0002448072,0.0000825321,0.0001807556,0.000134429,0.0001344164,0.0002871567,0.0001981549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995095,"about_ca_system_score_gemma":0.0001156573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001940181,"about_ca_topic_score_gemma":0.0003412083,"domain_scores_codex":[0.9998569,0.000037567,0.00001018978,0.00002253645,0.00002293194,0.00004996488],"domain_scores_gemma":[0.9999353,0.000009608081,0.0000143554,0.000009057361,0.000007981013,0.00002379085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003729697,0.00003411318,0.001338088,0.00002992208,0.00000717743,0.00005562404,0.00001202337,0.00002413648,0.9964597,0.00003369868,0.00004142555,0.001591071],"study_design_scores_gemma":[0.00008604524,0.002250726,0.1217482,0.00004005282,0.00005964797,0.0007341652,0.0001750216,0.0007352057,0.8710837,0.0001401915,0.002937471,0.000009596042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982634,0.0008336762,0.0001660865,0.00003984572,0.00001825798,0.00001094639,0.00007474927,0.000007965663,0.000585172],"genre_scores_gemma":[0.9987146,0.000345035,0.0001943623,0.00006946266,0.000007102191,0.000009333145,0.0001862981,0.000003386171,0.0004705687],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008341057,"threshold_uncertainty_score":0.002790391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157180722924485,"score_gpt":0.2594038047615178,"score_spread":0.2436857324690692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}