{"id":"W2049925231","doi":"10.1038/mi.2013.128","title":"Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity","year":2014,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; GlaxoSmithKline","keywords":"ISG15; Innate immune system; Interferon-stimulated gene; Biology; Interferon; Rhinovirus; Immunology; CXCL10; Proinflammatory cytokine; Cell biology; Immunity; Immune system; Secretion; Chemokine; Gene; Virus; Inflammation; Ubiquitin; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006798259,0.0005292944,0.000790235,0.0004069634,0.0008238052,0.00005121919,0.0008505649,0.0007856814,0.001046124],"category_scores_gemma":[0.0003593245,0.0004914156,0.0002783413,0.0002739619,0.0006829085,0.0002450482,0.0004081596,0.0012756,0.004064953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001211384,"about_ca_system_score_gemma":0.0001021701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001155965,"about_ca_topic_score_gemma":0.0000803189,"domain_scores_codex":[0.9958268,0.001752063,0.0006590041,0.0006137587,0.00006273147,0.001085573],"domain_scores_gemma":[0.9983979,0.0002834083,0.0002597899,0.0008232422,0.0002048796,0.00003078308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007143422,0.0003180113,0.0006724258,0.000009246058,0.0004903321,0.00000507662,0.0004802319,8.806273e-7,0.9771573,0.007742272,0.0008648018,0.01154511],"study_design_scores_gemma":[0.002927511,0.001952765,0.06168459,0.00002798528,0.00006081303,0.0001738386,0.0002054589,0.00001932469,0.9001849,0.0009264357,0.03123995,0.0005964041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866861,0.001010848,0.0001837665,0.0003087678,0.0019595,0.0002989194,0.00003004455,0.000396162,0.009125873],"genre_scores_gemma":[0.9934822,0.00003342654,0.0000521335,0.0003729204,0.0001013649,0.00004009685,0.0001290097,0.00007036817,0.00571851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07697234,"threshold_uncertainty_score":0.9998671,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157180722924485,"score_gpt":0.2594038047615178,"score_spread":0.2436857324690692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}