{"id":"W2050004994","doi":"10.1038/sj.mt.6300204","title":"Long-term Correction of β-Thalassemia With Minimal Cellular Requirement and Transplantation Modalities","year":2007,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Transplantation; Erythropoiesis; Thalassemia; Therapeutic index; Bone marrow; Medicine; Beta thalassemia; Ineffective erythropoiesis; Stem cell; Immunology; Haematopoiesis; Cancer research; Internal medicine; Biology; Pharmacology; Anemia; Drug; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001357507,0.0001021602,0.0001451065,0.0000726704,0.00003159023,0.00000590748,0.00002198974,0.00008249415,0.00002079365],"category_scores_gemma":[0.000002142569,0.00007648793,0.00003879708,0.00009332038,0.0000725441,0.00003103937,0.00000248628,0.00008083387,9.512364e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000195572,"about_ca_system_score_gemma":0.00002514598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004135588,"about_ca_topic_score_gemma":0.000007926904,"domain_scores_codex":[0.9993469,0.00001923232,0.0001671963,0.0001373576,0.000189206,0.0001401139],"domain_scores_gemma":[0.9997211,0.00001221979,0.00005496231,0.0001061214,0.00004949368,0.00005616531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002399487,0.0001931168,0.04021562,0.000169915,0.0001838157,0.0004178258,0.001912275,0.00003603901,0.9162176,0.00008318865,0.0000107629,0.03816031],"study_design_scores_gemma":[0.003442633,0.001290241,0.09005004,0.0001987668,0.00009693078,0.0001320995,0.0004643602,0.0001021911,0.9039692,0.00001790213,0.0001101696,0.0001254927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979182,0.002089657,0.0170974,0.0001095475,0.00007912301,0.0002746016,0.000001108328,0.00002284215,0.001143746],"genre_scores_gemma":[0.9981903,0.001198874,0.0002395399,0.0001272137,0.00001433213,0.000004177486,0.00002860207,0.00001699929,0.0001799129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04983442,"threshold_uncertainty_score":0.3119087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008705094086671755,"score_gpt":0.2451273291821925,"score_spread":0.2364222350955207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}