{"id":"W2050020385","doi":"10.1021/bi002699r","title":"Association of Calnexin with Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Medical Research Council Canada","keywords":"Calnexin; Nephrogenic diabetes insipidus; Endoplasmic reticulum; ER retention; Arginine vasopressin receptor 2; Cell biology; Mutant; Receptor; Biology; Golgi apparatus; Molecular biology; Chemistry; Calreticulin; Vasopressin; Biochemistry; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379166,0.0003298715,0.0002014877,0.0002454224,0.000146882,0.0002397035,0.0002418329,0.0003898364,0.0007470723],"category_scores_gemma":[0.0002147296,0.0002044939,0.0003278539,0.0001872983,0.0002601599,0.0001244588,0.0001641218,0.0003506881,0.0002598916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000384595,"about_ca_system_score_gemma":0.0001539242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007160058,"about_ca_topic_score_gemma":0.0007735047,"domain_scores_codex":[0.9997783,0.0000285408,0.00003336959,0.00004897752,0.00007381589,0.00003701858],"domain_scores_gemma":[0.999808,0.00004563514,0.00005059662,0.00002258371,0.00001208947,0.00006113668],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007819549,0.0000177112,0.0007001258,0.00001205815,0.00001027983,0.0005513937,0.0000161712,0.00003201552,0.9982823,0.00003668897,0.00001924734,0.00024381],"study_design_scores_gemma":[0.00007422396,0.0006196628,0.04619982,0.00001089504,0.00007457504,0.01340612,0.0001680949,0.003101967,0.9332565,0.0001240131,0.002938326,0.00002586155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991641,0.000155606,0.000354027,0.0000273001,0.00001024266,0.000003952935,0.0000946251,0.00001217337,0.0001779603],"genre_scores_gemma":[0.9973413,0.0001964778,0.0009772476,0.00004973462,0.000006622201,0.00001234467,0.0006204437,0.00001869821,0.000777052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007470723,"threshold_uncertainty_score":0.002790451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007344594196350382,"score_gpt":0.2014366840147307,"score_spread":0.1940920898183803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}