{"id":"W2050020385","doi":"10.1021/bi002699r","title":"Association of Calnexin with Wild Type and Mutant AVPR2 that Cause Nephrogenic Diabetes Insipidus","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Medical Research Council Canada","keywords":"Calnexin; Nephrogenic diabetes insipidus; Endoplasmic reticulum; ER retention; Arginine vasopressin receptor 2; Cell biology; Mutant; Receptor; Biology; Golgi apparatus; Molecular biology; Chemistry; Calreticulin; Vasopressin; Biochemistry; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007360848,0.0001141881,0.0001103069,0.00001531175,0.00003603775,0.000008834943,0.00005786198,0.0001897873,0.00001401198],"category_scores_gemma":[0.00002255181,0.0001020556,0.0000297629,0.00009823197,0.00004835242,0.000003750586,0.0000171662,0.00004959789,9.549103e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001822525,"about_ca_system_score_gemma":0.00005235122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008614738,"about_ca_topic_score_gemma":0.00001747556,"domain_scores_codex":[0.9993855,0.00001045593,0.000117411,0.0002019227,0.0001281845,0.0001564967],"domain_scores_gemma":[0.9995567,0.000005983634,0.0001074223,0.0001676885,0.0001091071,0.00005311678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000737896,0.00002645489,0.2003063,0.00002856896,0.00007935167,0.000001779879,0.00002775377,0.000005617442,0.7989298,0.000001719155,0.0003313352,0.0001876098],"study_design_scores_gemma":[0.0004368543,0.0001006886,0.02041933,0.00002099764,0.00005277889,0.000008874832,0.00006824445,0.0000212558,0.9754065,0.000009034238,0.003317603,0.0001378232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988725,0.0006571437,0.00002644208,0.0001110846,0.0000516159,0.00006425576,0.00000948299,0.00001026137,0.0001972547],"genre_scores_gemma":[0.9983559,0.0002708064,0.00005533241,0.00006424444,0.0001489771,0.000004982076,0.0001935413,0.00001437885,0.0008917931],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.179887,"threshold_uncertainty_score":0.4161707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007344594196350382,"score_gpt":0.2014366840147307,"score_spread":0.1940920898183803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}