{"id":"W2050041822","doi":"10.1056/nejmcibr1003522","title":"Acute Myeloid Leukemia and the Wnt Pathway","year":2010,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Myeloid leukemia; Medicine; Wnt signaling pathway; Leukemia; Myeloid; Cancer research; Signal transduction; Immunology; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002608327,0.0005995247,0.0002897111,0.0009945642,0.0002384203,0.0006197533,0.0002636988,0.0006268319,0.001622184],"category_scores_gemma":[0.000188751,0.0003138288,0.000278738,0.0004034188,0.0005348667,0.0003628086,0.0004002307,0.001025566,0.0003709082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005277845,"about_ca_system_score_gemma":0.0003708406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008725534,"about_ca_topic_score_gemma":0.001633839,"domain_scores_codex":[0.9996604,0.00007561895,0.00002897824,0.0000432513,0.0001229669,0.00006880359],"domain_scores_gemma":[0.9997737,0.00001870005,0.0001108101,0.0000196917,0.00001206064,0.00006500998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007446721,0.00006559036,0.0008687036,0.00004529321,0.00001653553,0.0002433132,0.00003114462,0.0001450149,0.993021,0.002081482,0.0001400881,0.002597116],"study_design_scores_gemma":[0.00037265,0.001113242,0.02640731,0.00006938561,0.0001843567,0.003736372,0.000205453,0.002673687,0.9485347,0.001946448,0.01472535,0.00003109109],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9860064,0.005445625,0.00360851,0.0006687192,0.00004711099,0.00003967106,0.0007504971,0.0001347276,0.003298744],"genre_scores_gemma":[0.9882959,0.002967351,0.002077305,0.0001268587,0.00001130474,0.00006526855,0.0006465979,0.00002603202,0.005783447],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001622184,"threshold_uncertainty_score":0.005426705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006246263204218282,"score_gpt":0.2422883630932471,"score_spread":0.2360420998890289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}