{"id":"W2050057383","doi":"10.1371/journal.pgen.1002380","title":"A High-Resolution Whole-Genome Map of Key Chromatin Modifications in the Adult Drosophila melanogaster","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Euchromatin; Heterochromatin; Chromatin; Genetics; Chromatin immunoprecipitation; Epigenomics; Drosophila melanogaster; Histone; Epigenetics; Histone code; Computational biology; Nucleosome; Gene; Gene expression; DNA methylation; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135688,0.0001445207,0.0001403755,0.00004961536,0.00005130978,0.00001338148,0.0004080729,0.0001335685,0.0000175742],"category_scores_gemma":[0.00001926377,0.0001229759,0.00006394785,0.00008266754,0.00009179159,0.000002338599,0.00009360273,0.00008398198,0.00002894052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001391038,"about_ca_system_score_gemma":0.00004196442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001932223,"about_ca_topic_score_gemma":0.0001029988,"domain_scores_codex":[0.9990014,0.00007041584,0.000337098,0.0002363607,0.0001455732,0.0002091012],"domain_scores_gemma":[0.999112,0.000008235882,0.0001447792,0.0005856208,0.0001102538,0.00003915692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002218123,0.0003070717,0.00104734,0.00004511261,0.00004302255,0.00000154488,0.001322516,0.000726254,0.9950642,0.001209309,0.0001495071,0.00006194554],"study_design_scores_gemma":[0.00374889,0.00226103,0.1118319,0.0001280725,0.0003393503,0.00005446712,0.002449717,0.0462808,0.8148862,0.01031236,0.006225322,0.001481925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976676,0.0003764227,0.0005217844,0.0002443267,0.00005905077,0.0002775396,0.0001435082,0.000005811475,0.0007039589],"genre_scores_gemma":[0.9934261,0.00009457221,0.005816408,0.0001429334,0.00009163628,0.00004618436,0.0002675825,0.00002349877,0.00009104463],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.180178,"threshold_uncertainty_score":0.5014812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840206058880216,"score_gpt":0.2066846985698889,"score_spread":0.1882826379810867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}