{"id":"W2050171234","doi":"10.1128/jb.00155-11","title":"Characterization of DNA Binding Sites of the ComE Response Regulator from Streptococcus mutans","year":2011,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Dental and Craniofacial Research; National Institutes of Health","keywords":"Biology; Footprinting; Direct repeat; Binding site; DNA footprinting; DNA; Streptococcus gordonii; Streptococcus mutans; Deoxyribonuclease I; Genetics; Genome; Molecular biology; DNA-binding protein; Gene; Transcription factor; Bacteria; Streptococcus; Base sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002284914,0.0004012671,0.000664159,0.000536786,0.0002137043,0.0002551448,0.0003557123,0.0004951778,0.001621732],"category_scores_gemma":[0.0008750453,0.0002815645,0.0005996213,0.000282696,0.0002223381,0.0002043516,0.0002592569,0.000567528,0.001296151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003678908,"about_ca_system_score_gemma":0.0003534428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002363192,"about_ca_topic_score_gemma":0.002138181,"domain_scores_codex":[0.9997348,0.00004050997,0.00001632501,0.00004943083,0.00011756,0.0000413356],"domain_scores_gemma":[0.9994557,0.0002055229,0.0000918782,0.00004409247,0.00007638896,0.0001264586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001118293,0.00003707845,0.0006233232,0.00006243587,0.000003712482,0.00006629235,0.00003022004,0.0001074133,0.9976845,0.00005223084,0.00001568437,0.001205394],"study_design_scores_gemma":[0.00002491836,0.0003093182,0.03520703,0.00002272572,0.00002063625,0.0004970131,0.00008915408,0.001943445,0.9593944,0.0001150969,0.002353591,0.00002271592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890968,0.001200189,0.007342491,0.00009926477,0.00001539157,0.00006195372,0.0007936026,0.0001105403,0.001279639],"genre_scores_gemma":[0.9838881,0.000370739,0.01027012,0.0001193494,0.00001961821,0.00006818345,0.00271049,0.00004506256,0.002508442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002363192,"threshold_uncertainty_score":0.005425215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0140344890165883,"score_gpt":0.2200637843160947,"score_spread":0.2060292952995064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}