{"id":"W2050198268","doi":"10.1016/s0008-6363(99)00357-0","title":"Heterogeneity in the response of vascular smooth muscle to heparin: altered signaling in heparin-resistant cells","year":2000,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Heparin; Vascular smooth muscle; Microgram; MAPK/ERK pathway; In vitro; Signal transduction; Internal medicine; In vivo; Cell culture; Endocrinology; Molecular biology; Biology; Cell biology; Biochemistry; Medicine; Smooth muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01023589,0.0001860272,0.0003694099,0.0002861684,0.0001129057,0.00004983766,0.0005715642,0.0001681827,0.00005027819],"category_scores_gemma":[0.0002646139,0.0001614028,0.0005464555,0.0008434606,0.0001377377,0.000007627914,0.0001636496,0.0003009349,0.00002529002],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000703239,"about_ca_system_score_gemma":0.0001525208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004856944,"about_ca_topic_score_gemma":0.0001500726,"domain_scores_codex":[0.9945834,0.00281092,0.0004271817,0.0006146586,0.000977098,0.0005867842],"domain_scores_gemma":[0.9982637,0.00008807026,0.00002965327,0.001332079,0.0001598801,0.0001266839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001071892,0.0001240961,0.0003401535,0.00005318445,0.0001283429,0.00007387282,0.0002789135,0.02613799,0.9597794,0.00001466871,0.00008510089,0.01191242],"study_design_scores_gemma":[0.001761759,0.0003559887,0.05391012,0.0001332487,0.0000272575,0.000006271714,0.000265178,0.0002972331,0.828816,0.00005955998,0.1140143,0.0003530643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930438,0.005315251,0.0002894804,0.0000805113,0.00002713505,0.0009071883,0.00001158427,0.000006778137,0.0003182254],"genre_scores_gemma":[0.9989619,0.0002789164,0.0003207227,0.00008245562,0.0001117817,0.0001449376,0.00002103261,0.00002986627,0.0000484332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1309634,"threshold_uncertainty_score":0.6581814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04095262163229518,"score_gpt":0.3143082256720224,"score_spread":0.2733556040397273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}