{"id":"W2050218188","doi":"10.1016/j.neuron.2012.06.033","title":"How Variable Clones Build an Invariant Retina","year":2012,"lang":"en","type":"article","venue":"Neuron","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":243,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Wellcome Trust; Engineering and Physical Sciences Research Council; U.S. Department of Energy","keywords":"Biology; Lineage (genetic); Progenitor cell; Retina; Neuroscience; Cell fate determination; Progenitor; Zebrafish; Cellular differentiation; Cell type; Transcription factor; Cell biology; Genetics; Stem cell; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008144706,0.000287834,0.0003851439,0.0006895774,0.0004748993,0.001911161,0.0006005928,0.0004880497,0.001759471],"category_scores_gemma":[0.002364108,0.0005636743,0.0003405275,0.000327973,0.0009326088,0.001286891,0.001037453,0.001219001,0.001112605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000564403,"about_ca_system_score_gemma":0.0005068965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006142061,"about_ca_topic_score_gemma":0.001147289,"domain_scores_codex":[0.9990043,0.0001117643,0.00007458073,0.0002859667,0.0003691234,0.0001543047],"domain_scores_gemma":[0.9985728,0.0003183758,0.0002253398,0.0004937227,0.0002097033,0.0001799348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001160865,0.00007870082,0.01376994,0.0001078607,0.00005761572,0.0005311538,0.0005241945,0.002112077,0.8168169,0.07687057,0.0009180553,0.08809683],"study_design_scores_gemma":[0.0001252071,0.0007441589,0.04023051,0.0001181312,0.0003613837,0.00602367,0.0007611198,0.01121771,0.8244945,0.03567139,0.08014435,0.0001078891],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.901294,0.001040954,0.07159401,0.0004637932,0.0001812773,0.0000694606,0.0001565934,0.0008033243,0.0243967],"genre_scores_gemma":[0.9634531,0.000780733,0.02673722,0.0003337379,0.00004349573,0.00005350296,0.0002201928,0.0005314805,0.00784648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001911161,"threshold_uncertainty_score":0.005886018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01108038190182712,"score_gpt":0.2252012023417256,"score_spread":0.2141208204398984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}