{"id":"W2050241712","doi":"10.1210/en.2006-0480","title":"Inhibition of Insulin-Stimulated Glycogen Synthesis by 5-Aminoimidasole-4-Carboxamide-1-β-d-Ribofuranoside-Induced Adenosine 5′-Monophosphate-Activated Protein Kinase Activation: Interactions with Akt, Glycogen Synthase Kinase 3-3α/β, and Glycogen Synthase in Isolated Rat Soleus Muscle","year":2006,"lang":"en","type":"article","venue":"Endocrinology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Internal medicine; Glycogen synthase; Endocrinology; Glycogen; Insulin; Glycogen branching enzyme; GSK-3; Glycogenesis; Protein kinase B; Chemistry; Biology; Phosphorylation; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418004,0.0005366146,0.0003197896,0.0001333844,0.0001270761,0.0001671209,0.0001900471,0.00024549,0.0009264908],"category_scores_gemma":[0.00008610175,0.000161051,0.0003494704,0.0001203002,0.0001818577,0.0001725594,0.0001366767,0.0004591879,0.0002184594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001774405,"about_ca_system_score_gemma":0.0002037877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005454791,"about_ca_topic_score_gemma":0.001166601,"domain_scores_codex":[0.9998996,0.00002166158,0.00001210725,0.00001924377,0.00001710678,0.00003010402],"domain_scores_gemma":[0.9999259,0.00001554981,0.00002314441,0.000008149221,0.000008439266,0.00001880385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005735594,0.0000459101,0.0001508714,0.00007137483,0.00001172265,0.00004801207,0.000009491954,0.00004181183,0.998052,0.00001623296,0.00001779041,0.0009611979],"study_design_scores_gemma":[0.00009575718,0.001273925,0.01025322,0.00001047092,0.00003861184,0.0001824341,0.00002902592,0.0005911249,0.9867012,0.00001770327,0.0008002002,0.000006361528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947836,0.003524458,0.0007491609,0.00006131167,0.00002620774,0.00001715778,0.0001296594,0.00002959802,0.000678825],"genre_scores_gemma":[0.9946314,0.002286852,0.001481256,0.00005579274,0.00001729427,0.00005957685,0.0004095618,0.00001080242,0.001047424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009264908,"threshold_uncertainty_score":0.003099442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008543984231820527,"score_gpt":0.2258248401037606,"score_spread":0.21728085587194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}