{"id":"W2050244237","doi":"10.1016/j.jhep.2011.12.009","title":"Relationship between baseline hepatic status and outcome, and effect of sorafenib on liver function: SHARP trial subanalyses","year":2012,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"Onyx Pharmaceuticals; Bayer HealthCare","keywords":"Sorafenib; Hepatocellular carcinoma; Bilirubin; Internal medicine; Gastroenterology; Medicine; Liver function; Alpha-fetoprotein; Alanine aminotransferase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110803,0.0001557197,0.0007927712,0.0003060787,0.00005455751,0.000006823129,0.00003003996,0.0001466561,0.00008879018],"category_scores_gemma":[0.000824044,0.0001048064,0.0001683255,0.0001305815,0.00008361982,0.0001191335,0.00001847483,0.0002575878,0.000007079914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004176622,"about_ca_system_score_gemma":0.00005031186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003118506,"about_ca_topic_score_gemma":0.000005561104,"domain_scores_codex":[0.9983472,0.0004656254,0.0006474942,0.0001092933,0.0002066912,0.0002237008],"domain_scores_gemma":[0.9971121,0.002014952,0.0004091621,0.0001208055,0.0000912164,0.0002517604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01129026,0.0001230174,0.9856172,0.0001470073,0.00024774,0.00004617867,0.00008978847,8.284868e-8,0.00002722512,0.00005352365,0.0001119726,0.002245979],"study_design_scores_gemma":[0.02135297,0.007101657,0.9671082,0.000043396,0.002772128,0.0002025831,0.0000164764,0.0001045079,0.0007749334,0.00003375822,0.00040281,0.00008653755],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937089,0.005265628,0.00007363338,0.0003491766,0.0002138609,0.0002940653,0.000006268224,0.000006761338,0.0000817018],"genre_scores_gemma":[0.9991314,0.0001138837,0.0002351408,0.00006952623,0.000372335,0.000005116072,0.00001506237,0.0000134333,0.00004403649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01850898,"threshold_uncertainty_score":0.4273881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1370066727138807,"score_gpt":0.3350274567965549,"score_spread":0.1980207840826742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}