{"id":"W2050265892","doi":"10.1016/j.clim.2006.04.317","title":"Sa.85. Gene Therapy for Purine Nucleoside Phosphorylase Deficiency","year":2006,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Purine nucleoside phosphorylase; Purine; Genetic enhancement; Nucleoside; Glycogen phosphorylase; Gene; Medicine; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003857242,0.0001930726,0.0002705167,0.00003337892,0.0001098712,0.00002052478,0.0004242179,0.0004791593,0.00005959927],"category_scores_gemma":[0.000314368,0.0001671421,0.0003281829,0.00009060499,0.0006304266,0.000002488033,0.0002160229,0.0002319085,0.00005968775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001069962,"about_ca_system_score_gemma":0.00009923525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005062444,"about_ca_topic_score_gemma":0.0000133052,"domain_scores_codex":[0.9981471,0.0001078539,0.0005092487,0.000611828,0.000102314,0.000521698],"domain_scores_gemma":[0.9990185,0.00007364347,0.00009772741,0.0005670359,0.0001567039,0.00008634876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007343843,0.0005877138,0.001178935,0.00000582374,0.00007640939,0.000007151746,0.000001692801,0.000002165988,0.9702992,0.00064403,0.008345749,0.01811676],"study_design_scores_gemma":[0.002239286,0.001385985,0.007896631,0.000003313883,0.00001346632,0.00002046089,0.000005235447,0.00001293109,0.8002093,0.001414594,0.1865763,0.0002225125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820402,0.01260514,0.002638529,0.000924429,0.0003238895,0.0004320177,0.0000299416,0.00002929741,0.0009766226],"genre_scores_gemma":[0.991641,0.002454695,0.001991309,0.0007828657,0.0005254986,0.0001140259,0.000368733,0.00004328701,0.002078602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1782306,"threshold_uncertainty_score":0.6815857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02758294791157592,"score_gpt":0.3433982590196939,"score_spread":0.315815311108118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}