{"id":"W2050311121","doi":"10.1093/nar/gks745","title":"Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability","year":2012,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences","keywords":"Telomere; Biology; Telomere-binding protein; Cockayne syndrome; Telomerase; Shelterin; Premature aging; Chromatin; DNA damage; DNA repair; Cell biology; Molecular biology; Gene knockdown; Genetics; DNA; Transcription factor; DNA-binding protein; Nucleotide excision repair; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009343408,0.0003649714,0.000173564,0.0004378942,0.000269472,0.0003020191,0.0001421281,0.0003118288,0.0008884311],"category_scores_gemma":[0.0001684193,0.0001799132,0.0001485891,0.0001664386,0.0001722415,0.0001199084,0.0002329874,0.000233456,0.0004174765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002697174,"about_ca_system_score_gemma":0.00008864284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009042167,"about_ca_topic_score_gemma":0.001033337,"domain_scores_codex":[0.9999107,0.0000183993,0.00000557104,0.00002504804,0.00002280433,0.00001747315],"domain_scores_gemma":[0.9999077,0.000009279042,0.00003333682,0.000007727714,0.000008263087,0.00003368156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001076186,0.00001642642,0.003835456,0.00001739577,0.00001235771,0.0002103356,0.00001975191,0.0000526039,0.9936404,0.00006652307,0.00009493469,0.001926285],"study_design_scores_gemma":[0.0001260467,0.0006542305,0.362665,0.00002823146,0.00006543866,0.00660379,0.0001678084,0.003698512,0.6134294,0.0004760709,0.01205208,0.00003337588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957373,0.002730184,0.0006640219,0.00006538897,0.000006934577,0.000003218607,0.00006098044,0.00005501102,0.0006768975],"genre_scores_gemma":[0.9976482,0.0004951592,0.0004707069,0.00001917253,0.000005893343,0.000005931001,0.0001668654,0.000009747638,0.001178184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009042167,"threshold_uncertainty_score":0.002972126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05016199738857677,"score_gpt":0.3220981773210125,"score_spread":0.2719361799324357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}