{"id":"W2050318990","doi":"10.1074/jbc.m111.307884","title":"Adenine Aminohydrolase from Leishmania donovani","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Ste. Anne's Hospital","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Leishmania donovani; Hypoxanthine; Molecular biology; Adenosine deaminase; Biochemistry; Purine metabolism; Adenosine; Enzyme; Leishmaniasis; Genetics; Visceral leishmaniasis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000439459,0.0001681208,0.0005246596,0.00003407488,0.00005092018,0.00001599654,0.0001984256,0.0001985764,0.001416145],"category_scores_gemma":[0.001114626,0.0001016337,0.0002395987,0.0001270287,0.0001717825,0.0001174662,0.0001242104,0.0006269906,0.00005809896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001159756,"about_ca_system_score_gemma":0.00005152644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006416963,"about_ca_topic_score_gemma":1.255254e-7,"domain_scores_codex":[0.9985123,0.00003943151,0.0005039782,0.0001411055,0.0003964318,0.0004067006],"domain_scores_gemma":[0.9986284,0.0002155659,0.0002741667,0.0001981525,0.0002227798,0.0004609691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004493208,0.0004324438,0.2596203,0.00003177249,0.0002151205,0.0002247363,0.00004999726,2.75082e-7,0.7321544,0.000004561305,0.005033261,0.001783779],"study_design_scores_gemma":[0.002014018,0.0004212816,0.3815184,0.0001188914,0.0001094144,0.001179047,0.000262638,0.000008466882,0.5872285,0.0001217282,0.02682224,0.0001954239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891914,0.00525385,0.00003877326,0.001227944,0.0001182721,0.00006030576,0.00001104959,0.00002085257,0.004077544],"genre_scores_gemma":[0.9950277,0.0006632794,0.00133356,0.0002442414,0.002265483,0.000002610611,0.00001157842,0.00001121319,0.0004403636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.144926,"threshold_uncertainty_score":0.9994967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05358824390621284,"score_gpt":0.3137948506769202,"score_spread":0.2602066067707073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}