{"id":"W2050332780","doi":"10.1002/btpr.302","title":"Doubling the catabolic reducing power (NADH) output of <i>Escherichia coli</i> fermentation for production of reduced products","year":2009,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Association for the Study of the Liver","keywords":"Fermentation; Escherichia coli; Operon; Biochemistry; Catabolism; Anaerobic exercise; Chemistry; Pyruvate dehydrogenase complex; Formate; Dehydrogenase; Biology; Metabolism; Enzyme; Catalysis; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002501715,0.0005425179,0.0003716995,0.0001810999,0.0001550956,0.000615684,0.0002679443,0.0001990658,0.0007526793],"category_scores_gemma":[0.0003155753,0.0001624138,0.000237359,0.0002894088,0.0001871202,0.0003488172,0.0003401536,0.0004920065,0.0004566882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004873168,"about_ca_system_score_gemma":0.0003773727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007815548,"about_ca_topic_score_gemma":0.0008049065,"domain_scores_codex":[0.9996645,0.00006562358,0.00002865064,0.00005144432,0.0001255746,0.00006419248],"domain_scores_gemma":[0.9998412,0.000039071,0.00003306982,0.00002526035,0.00003059979,0.00003084022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004559306,0.00002262062,0.0002141331,0.00002249621,0.000001843264,0.00001398929,0.000008674063,0.0000881068,0.9980003,0.0001172617,0.00003185702,0.001433176],"study_design_scores_gemma":[0.000002763665,0.00005490466,0.0006221623,0.000003106165,0.000005154056,0.0000449641,0.00001215604,0.0004362322,0.9977723,0.00004182523,0.001001237,0.000003247694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826134,0.0004706613,0.01290004,0.0002506679,0.00003199517,0.00004208334,0.0004700522,0.0002003153,0.003020842],"genre_scores_gemma":[0.9713567,0.0007495964,0.02373974,0.00004933696,0.000006946736,0.00004907394,0.00151966,0.00008997486,0.002439105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007815548,"threshold_uncertainty_score":0.003535688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01047851640932358,"score_gpt":0.2483355688717715,"score_spread":0.2378570524624479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}