{"id":"W2050346490","doi":"10.1371/journal.pgen.1001295","title":"Phosphoinositide Regulation of Integrin Trafficking Required for Muscle Attachment and Maintenance","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Michael Smith Health Research BC; University of California, San Diego; March of Dimes Foundation; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Hellman Family Foundation","keywords":"Sarcolemma; Cell biology; Biology; Myocyte; Endosome; Integrin; Endocytic cycle; Myogenesis; Integrin-linked kinase; Compartmentalization (fire protection); Cell; Endocytosis; Kinase; Protein kinase A; Biochemistry; Intracellular; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006982468,0.0002794181,0.0001254011,0.0001753633,0.0001843091,0.0003821079,0.0001564481,0.0002098401,0.0004796416],"category_scores_gemma":[0.0000822298,0.0001350067,0.000129767,0.0001163324,0.0002450749,0.0002252739,0.0002004555,0.0002636085,0.0003118047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004979194,"about_ca_system_score_gemma":0.0002008528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007028502,"about_ca_topic_score_gemma":0.001249243,"domain_scores_codex":[0.9999459,0.000006380562,0.000005241314,0.00001435306,0.00001782551,0.0000102644],"domain_scores_gemma":[0.999949,0.000005219084,0.00002370106,0.000005467228,0.000005051395,0.00001159284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000291315,0.000003286166,0.0002858752,0.00001104698,0.000001317123,0.00005638903,0.000005909438,0.00004813155,0.998475,0.0002589106,0.00001519295,0.0008097359],"study_design_scores_gemma":[0.000008602805,0.0000594165,0.01939009,0.000006168727,0.00001010484,0.0005693886,0.00004239257,0.002294193,0.9752131,0.0002971315,0.002104987,0.000004478178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929015,0.001970325,0.003332486,0.0001036245,0.00001231318,0.000009942577,0.0001633649,0.00006360606,0.001442833],"genre_scores_gemma":[0.9962607,0.0007681077,0.001479824,0.00002021599,0.000004798853,0.000009179421,0.0001822828,0.00001232142,0.001262564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007028502,"threshold_uncertainty_score":0.003612697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02883930020972059,"score_gpt":0.2307937203438294,"score_spread":0.2019544201341088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}