{"id":"W2050346490","doi":"10.1371/journal.pgen.1001295","title":"Phosphoinositide Regulation of Integrin Trafficking Required for Muscle Attachment and Maintenance","year":2011,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Michael Smith Health Research BC; University of California, San Diego; March of Dimes Foundation; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Hellman Family Foundation","keywords":"Sarcolemma; Cell biology; Biology; Myocyte; Endosome; Integrin; Endocytic cycle; Myogenesis; Integrin-linked kinase; Compartmentalization (fire protection); Cell; Endocytosis; Kinase; Protein kinase A; Biochemistry; Intracellular; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007777588,0.00008756897,0.00009841466,0.00001959233,0.00002992873,0.000003950987,0.00006269517,0.00008362637,0.00001170362],"category_scores_gemma":[0.00001074161,0.00008774974,0.00005111733,0.00002805239,0.00005476796,0.000002069105,0.00001796237,0.00002592365,3.930169e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006167331,"about_ca_system_score_gemma":0.0000163668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003957966,"about_ca_topic_score_gemma":0.00002256565,"domain_scores_codex":[0.9994239,0.00001055613,0.000182362,0.0001905863,0.00006644581,0.0001261043],"domain_scores_gemma":[0.9996448,0.000004514427,0.00007346767,0.0001625368,0.00007689162,0.00003778878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009505673,0.0000556017,0.00481575,0.00004885051,0.00002551373,3.438658e-7,0.0003260322,0.00002046964,0.9924393,0.0001621113,0.0000211058,0.001989823],"study_design_scores_gemma":[0.0004418551,0.0002937081,0.01992156,0.00003046522,0.0000416726,0.000001665072,0.00008190385,0.001742356,0.9746999,0.0001657727,0.002465993,0.0001131665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9694157,0.0006997784,0.02925028,0.00001378175,0.00005020605,0.0002374376,0.00001471499,0.000006998089,0.0003110901],"genre_scores_gemma":[0.994215,0.0002151184,0.0050559,0.00002227166,0.00004805085,0.00001652912,0.0003110532,0.00001570033,0.0001004136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02479925,"threshold_uncertainty_score":0.3578331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02883930020972059,"score_gpt":0.2307937203438294,"score_spread":0.2019544201341088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}