{"id":"W2050347354","doi":"10.1185/030079904125004006","title":"Triple nucleoside treatment with abacavir plus the lamivudine/ zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naïve adults: results of a 48-week open-label, equivalence trial (CNA3014)","year":2004,"lang":"en","type":"article","venue":"Current Medical Research and Opinion","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Medicine; Abacavir; Lamivudine; Indinavir; Zidovudine; Regimen; Tolerability; Population; Internal medicine; Viral load; Intention-to-treat analysis; Gastroenterology; Randomized controlled trial; Immunology; Adverse effect; Human immunodeficiency virus (HIV); Antiretroviral therapy; Viral disease; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001578003,0.0009829552,0.002845329,0.0002967822,0.0002858393,0.0008010665,0.0008826859,0.001423716,0.004866385],"category_scores_gemma":[0.002362374,0.0004093397,0.001235346,0.0003157691,0.0009054431,0.0009187654,0.0003693061,0.00237307,0.0005554254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005173908,"about_ca_system_score_gemma":0.0006049117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008531827,"about_ca_topic_score_gemma":0.001309184,"domain_scores_codex":[0.9989551,0.0006852833,0.00007368628,0.000137455,0.0000625204,0.00008584372],"domain_scores_gemma":[0.9984755,0.0004825073,0.0003689819,0.0001024144,0.0000892656,0.0004812899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9708547,0.005641771,0.0006909337,0.0003394337,0.0006664718,0.00002200635,0.00004374615,0.0001505106,0.001895657,0.00004845898,0.0002739603,0.01937237],"study_design_scores_gemma":[0.8356988,0.1574697,0.004663594,0.00004007979,0.0006238751,0.00004901452,0.00003024804,0.0005576456,0.0004557957,0.0001130669,0.0002844058,0.00001373336],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995719,0.002219782,0.0001683475,0.0002302385,0.0001468671,0.0004711777,0.0002606805,0.00003142475,0.0007525042],"genre_scores_gemma":[0.9960866,0.001092067,0.0006090115,0.0003896275,0.0002214892,0.0004830382,0.0003998549,0.000008286685,0.0007101106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004866385,"threshold_uncertainty_score":0.0162797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1849623011101594,"score_gpt":0.4390745304334409,"score_spread":0.2541122293232815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}