{"id":"W2050347354","doi":"10.1185/030079904125004006","title":"Triple nucleoside treatment with abacavir plus the lamivudine/ zidovudine combination tablet (COM) compared to indinavir/COM in antiretroviral therapy-naïve adults: results of a 48-week open-label, equivalence trial (CNA3014)","year":2004,"lang":"en","type":"article","venue":"Current Medical Research and Opinion","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"Medicine; Abacavir; Lamivudine; Indinavir; Zidovudine; Regimen; Tolerability; Population; Internal medicine; Viral load; Intention-to-treat analysis; Gastroenterology; Randomized controlled trial; Immunology; Adverse effect; Human immunodeficiency virus (HIV); Antiretroviral therapy; Viral disease; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00195171,0.0003229816,0.0007575366,0.0004217923,0.0002542614,0.00009506188,0.0004677151,0.0001333704,0.00003946366],"category_scores_gemma":[0.0007463697,0.000185241,0.00004956789,0.001176447,0.0004609842,0.0002176923,0.0003006872,0.000600434,0.00002910725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006751559,"about_ca_system_score_gemma":0.00125633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009989588,"about_ca_topic_score_gemma":0.0002144091,"domain_scores_codex":[0.9956035,0.0003317606,0.0007715808,0.0006579368,0.001905804,0.0007294164],"domain_scores_gemma":[0.9980227,0.0004803766,0.0001624279,0.0004375177,0.0002949791,0.0006019992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4134152,0.03195945,0.01308303,0.0005091488,0.000452808,0.0002892919,0.009002827,0.000007581929,0.0003825647,0.001634306,0.01018374,0.51908],"study_design_scores_gemma":[0.8759046,0.05552301,0.02007596,0.008994119,0.00005775275,0.00004106234,0.001907302,0.00147349,0.002643233,0.0007083429,0.03207128,0.0005998771],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729119,0.002339812,0.0001272504,0.01850859,0.0003822291,0.005285567,0.00008655847,0.00003070659,0.0003274041],"genre_scores_gemma":[0.9895766,0.008430676,0.0001884068,0.00005799048,0.0001576511,0.000512853,0.0005379099,0.00002713639,0.0005107655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5184801,"threshold_uncertainty_score":0.7553907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1849623011101594,"score_gpt":0.4390745304334409,"score_spread":0.2541122293232815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}