{"id":"W2050366912","doi":"10.1016/j.cjca.2014.07.246","title":"SIRTUIN 1 PLAYS A CRUCIAL ROLE IN MODULATING THE PULMONARY AND SYSTEMIC HYPOXIC RESPONSE IN MICE: NOVEL ROLE FOR HYPOXIA INDUCIBLE FACTOR-3ALPHA?","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Hypoxia (environmental); Sirtuin; Hypoxia-inducible factors; Cancer research; Cell biology; Gene; Oxygen; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003617069,0.0006647016,0.0005929032,0.0004086911,0.0003142321,0.0006575954,0.0006978927,0.0008960245,0.002741402],"category_scores_gemma":[0.0001976628,0.000478233,0.0005083101,0.0002107044,0.0009536427,0.0005851388,0.0003097497,0.001679382,0.0005285595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005934513,"about_ca_system_score_gemma":0.0004750449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001233302,"about_ca_topic_score_gemma":0.003148012,"domain_scores_codex":[0.9997452,0.00002701731,0.0000142181,0.00006572709,0.0000568093,0.00009100403],"domain_scores_gemma":[0.9996859,0.00001286656,0.0001178549,0.00003627558,0.0000260854,0.0001209807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001179047,0.00005537627,0.001029212,0.00006945648,0.00002888565,0.0002313168,0.00003732779,0.00006189334,0.991794,0.001126098,0.0003273805,0.004060044],"study_design_scores_gemma":[0.0004431982,0.001224734,0.06798622,0.00008512416,0.0004203329,0.001799541,0.0006075438,0.002781223,0.9026972,0.002462198,0.01941988,0.00007286466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9585856,0.01576254,0.01373876,0.004997013,0.000732229,0.00005245836,0.0009647985,0.0005348597,0.004631777],"genre_scores_gemma":[0.9873778,0.00282906,0.002108709,0.0004803248,0.00009952261,0.00003134271,0.0003105273,0.00007982937,0.006682782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002741402,"threshold_uncertainty_score":0.00917089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01218865747751037,"score_gpt":0.2275260047060647,"score_spread":0.2153373472285543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}