{"id":"W2050466071","doi":"10.1101/gr.077115.108","title":"Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, <i>TFPI2</i>/<i>Tfpi2</i>, which requires EHMT2 and EED for allelic-silencing","year":2008,"lang":"en","type":"article","venue":"Genome Research","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Medical Research Council; Sickkids Research Institute; Medical Research Council Canada; Agence Nationale de la Recherche; Hospital for Sick Children; Wellcome Trust; Genome Canada; Wellbeing of Women; March of Dimes Foundation","keywords":"Biology; Genomic imprinting; Histone; Genetics; DNA methylation; Imprinting (psychology); Molecular biology; Histone methylation; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001100385,0.0003253385,0.0007749202,0.0004971725,0.0005696013,0.00007114153,0.0003895869,0.0002287499,0.00006067876],"category_scores_gemma":[0.00009282102,0.0003227618,0.0001756371,0.0008845302,0.0006261962,0.0000171869,0.0006481056,0.0002584185,0.000003258536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005972252,"about_ca_system_score_gemma":0.0001341383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001032794,"about_ca_topic_score_gemma":0.00008819497,"domain_scores_codex":[0.9967492,0.0002420542,0.0006565418,0.001004251,0.0004914913,0.0008564727],"domain_scores_gemma":[0.9980606,0.00008887005,0.0002061613,0.0006782102,0.0006838657,0.0002822998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007634789,0.0001176557,0.007095954,0.0001179595,0.0006519198,0.000004511871,0.001106173,0.00005716157,0.9904281,0.00004689315,0.0001823752,0.0001149138],"study_design_scores_gemma":[0.002504235,0.002068277,0.1462227,0.00005000478,0.0001817561,0.0001494316,0.001375197,0.0008046733,0.8435687,0.00005429316,0.002337689,0.0006829635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994373,0.003554845,0.0003777454,0.00006968756,0.00002581779,0.001092093,0.0001606037,0.00001609001,0.0003300783],"genre_scores_gemma":[0.994319,0.002013979,0.002171126,0.00002297653,0.0001579029,0.000146631,0.0003741614,0.00004286633,0.0007513093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1468594,"threshold_uncertainty_score":0.9999225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07297829103464612,"score_gpt":0.3466313032178899,"score_spread":0.2736530121832438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}