{"id":"W2050551048","doi":"10.1371/journal.pgen.1003890","title":"Nuclear Fragile X Mental Retardation Protein Is localized to Cajal Bodies","year":2013,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Gene isoform; Cajal body; RNA-binding protein; Cell biology; Ribonucleoprotein; Messenger RNA; Translation (biology); Alternative splicing; RNA; Nuclear localization sequence; RNA splicing; Molecular biology; Nucleus; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003365769,0.0001924158,0.0001266988,0.00004070373,0.000111701,0.0000585416,0.0002140121,0.0001081524,0.0004304504],"category_scores_gemma":[0.0000223747,0.0001981664,0.00005854994,0.00006272724,0.0000498939,0.000003369083,0.0002187939,0.00006260919,0.0004985863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001499744,"about_ca_system_score_gemma":0.0000323669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001032369,"about_ca_topic_score_gemma":0.00001387962,"domain_scores_codex":[0.9988477,0.00003109547,0.0002150685,0.0003996513,0.0002142207,0.0002923113],"domain_scores_gemma":[0.9993898,0.000001925339,0.00004758568,0.0003184727,0.00009182147,0.000150452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002224337,0.00007913772,0.0005507832,0.00001393482,0.00003954818,5.477254e-7,0.0003030088,0.00001943516,0.9781907,0.000005819697,0.01945048,0.001324342],"study_design_scores_gemma":[0.0003841168,0.0003509297,0.00173356,0.00001271714,0.00001225332,0.00000285506,0.0001768499,0.0006332815,0.9216049,0.00008438811,0.07470684,0.0002973179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965903,0.0002370799,0.00005918605,0.0009130582,0.00008840951,0.0008043596,0.00002800934,0.00001976369,0.001259852],"genre_scores_gemma":[0.9926746,0.0001550686,0.003691077,0.002140176,0.00004117124,0.00009909971,0.00009786975,0.0000513861,0.001049535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05658582,"threshold_uncertainty_score":0.808099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083869080199514,"score_gpt":0.212874651012088,"score_spread":0.2020359602100929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}