{"id":"W2050644751","doi":"10.1016/j.ejca.2011.05.019","title":"Early stopping rules in oncology: Considerations for clinicians","year":2011,"lang":"en","type":"review","venue":"European Journal of Cancer","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Clinical trial; Harm; Medicine; Clinical Practice; Intensive care medicine; Clinical Oncology; Medical physics; Cancer; Oncology; Family medicine; Internal medicine; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.01237071,0.0002914994,0.00296835,0.0002368851,0.00005555079,0.00004239912,0.0003940279,0.0001687019,0.000413231],"category_scores_gemma":[0.09884424,0.000215989,0.0008354751,0.0001116999,0.0001406548,0.00006106142,0.00006857308,0.001081213,0.00003450874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002039219,"about_ca_system_score_gemma":0.0008805554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003060534,"about_ca_topic_score_gemma":0.00001452359,"domain_scores_codex":[0.990269,0.0051778,0.0038337,0.0002452054,0.000199104,0.0002751861],"domain_scores_gemma":[0.9282258,0.06774738,0.003246569,0.0002663384,0.0003698113,0.0001441019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000337298,0.00009236216,0.000002146389,0.001979925,0.000270111,0.0001563583,0.0001960222,2.610477e-7,7.975569e-8,0.01635341,0.005733855,0.9751818],"study_design_scores_gemma":[0.0007294742,0.0003687172,0.00001268204,0.0126379,0.001114045,0.00003478125,0.00001238679,5.087331e-7,1.952015e-7,0.2058509,0.7790585,0.0001799366],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000004975416,0.9711198,0.01890291,0.0001549644,0.002445457,0.0007424317,0.0002060892,0.00001393481,0.006409418],"genre_scores_gemma":[0.000001222621,0.6057079,0.3927451,0.0001027441,0.001203764,0.000017611,2.690289e-7,0.00007298754,0.0001483569],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9750018,"threshold_uncertainty_score":0.9087466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.866584728659454,"score_gpt":0.6631963191333864,"score_spread":0.2033884095260676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}