{"id":"W2050657418","doi":"10.1310/hct1101-39","title":"A Meta-Analysis of Six Placebo-Controlled Trials of Thiazolidinedione Therapy for HIV Lipoatrophy","year":2010,"lang":"en","type":"review","venue":"HIV Clinical Trials","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"National Center for Research Resources; U.S. Public Health Service; National Institutes of Health; Amgen; National Institute of Diabetes and Digestive and Kidney Diseases; Gilead Sciences; National Institute of Allergy and Infectious Diseases; Medical Research Council; ACT Government; Bristol-Myers Squibb; GlaxoSmithKline; National Health and Medical Research Council","keywords":"Pioglitazone; Rosiglitazone; Medicine; Placebo; Thiazolidinedione; Stavudine; Internal medicine; Lipoatrophy; Body mass index; Zidovudine; Urology; Endocrinology; Gastroenterology; Pharmacology; Diabetes mellitus; Human immunodeficiency virus (HIV); Antiretroviral therapy; Type 2 diabetes; Viral load; Insulin; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01732977,0.003412073,0.0165198,0.004264886,0.0008336524,0.003805779,0.001803338,0.002493369,0.003678112],"category_scores_gemma":[0.0306158,0.001469375,0.04215649,0.004551911,0.0007534885,0.001301041,0.001158981,0.002474729,0.000279302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001960634,"about_ca_system_score_gemma":0.001661818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003996095,"about_ca_topic_score_gemma":0.007566742,"domain_scores_codex":[0.9815493,0.01200392,0.003008364,0.001933435,0.001127006,0.000378033],"domain_scores_gemma":[0.9821734,0.01334689,0.002719179,0.0007228736,0.0007431073,0.0002944605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01407377,0.00003751542,0.004629152,0.02667418,0.9480436,0.00009197537,0.00002227392,0.0007152434,0.0002705857,0.00005262334,0.0003054659,0.005083613],"study_design_scores_gemma":[0.002933981,0.0004004712,0.003629936,0.001379468,0.9906306,0.00005564919,0.00001582385,0.0002540208,0.00010365,0.0001055022,0.0004798258,0.00001119774],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04861517,0.9457967,0.001814665,0.0005147525,0.0005449856,0.0004818165,0.001479877,0.0001128127,0.0006391946],"genre_scores_gemma":[0.7598747,0.2304707,0.004219356,0.00138488,0.0004600842,0.001051115,0.00185673,0.00007801426,0.0006044435],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01732977,"threshold_uncertainty_score":0.09164965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.6418827890290362,"score_gpt":0.5873134464127776,"score_spread":0.05456934261625856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}