{"id":"W2050694730","doi":"10.1371/journal.ppat.1002257","title":"Hsp90 Governs Dispersion and Drug Resistance of Fungal Biofilms","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":284,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; American Heart Association; Burroughs Wellcome Fund","keywords":"Biofilm; Candida albicans; Microbiology; Hsp90; Biology; Corpus albicans; Drug resistance; Antifungal drug; Cell biology; Heat shock protein; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145585,0.0001012965,0.0001176628,0.00003031386,0.00005185378,0.000005401954,0.0001433267,0.00008997825,0.00005948597],"category_scores_gemma":[0.0001163491,0.00009215996,0.0000490184,0.00007010306,0.0001057807,0.000003029509,0.0001598515,0.00007393056,0.00001151206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009651986,"about_ca_system_score_gemma":0.00004388613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002322718,"about_ca_topic_score_gemma":0.00005612809,"domain_scores_codex":[0.9991106,0.00006883335,0.0001411823,0.0002779712,0.0001809938,0.0002204487],"domain_scores_gemma":[0.9994307,0.000007677192,0.00004015433,0.0003443387,0.00007337417,0.0001037697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001096835,0.00008823727,0.01302135,0.00005609915,0.00002611132,0.0000109017,0.0001631706,6.690853e-8,0.9856422,0.000095459,0.0004181227,0.0003686282],"study_design_scores_gemma":[0.0002236352,0.0001107021,0.008561904,0.00002543403,0.00001197964,0.000003475114,0.00006961088,0.0000114304,0.9873214,0.00002589958,0.00351761,0.0001168899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940355,0.0007050631,0.00007855122,0.00005895453,0.00002092138,0.000186439,0.0001115716,0.000007704498,0.004795273],"genre_scores_gemma":[0.9954294,0.0003141536,0.002008419,0.00002517232,0.00004768444,0.00001600169,0.00002019972,0.0000191846,0.002119802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004459442,"threshold_uncertainty_score":0.3758174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282430825015664,"score_gpt":0.2422968842660502,"score_spread":0.2194725760158936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}