{"id":"W2050704917","doi":"10.1128/mbio.00297-11","title":"A Bilayer-Couple Model of Bacterial Outer Membrane Vesicle Biogenesis","year":2012,"lang":"en","type":"article","venue":"mBio","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":216,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Cystic Fibrosis Canada","keywords":"Bacterial outer membrane; Vesicle; Membrane curvature; Biogenesis; Membrane; Biophysics; Lipid bilayer; Inner membrane; Chemistry; Cell biology; Bilayer; Biology; Biochemistry; Escherichia coli","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001166714,0.0001038036,0.0001910697,0.00006361337,0.00007085768,0.000006613403,0.00008467624,0.0001586493,0.001981018],"category_scores_gemma":[0.00001319555,0.00008549635,0.0000817633,0.00007907287,0.00004510911,0.0001264729,0.00005018763,0.00005284377,0.0003389988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001048333,"about_ca_system_score_gemma":0.00001777044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002034467,"about_ca_topic_score_gemma":0.00001761469,"domain_scores_codex":[0.999397,0.00003663597,0.0001953852,0.0001121714,0.000008730938,0.0002500793],"domain_scores_gemma":[0.9996501,0.00002155575,0.00006671786,0.0002027367,0.00003815442,0.00002070082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009040959,0.0001737401,0.003334692,0.000009249458,0.00006204835,4.268947e-8,0.0001838153,0.000004781876,0.9935808,0.0002194457,0.001363747,0.0009772812],"study_design_scores_gemma":[0.0006684898,0.00005524648,0.004184697,0.000005390214,0.00004046328,0.00001275295,0.00002190106,0.00002531707,0.9744211,0.00001978189,0.02042841,0.0001164691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99729,0.0003035415,0.0001294744,0.00006787489,0.001600676,0.00008779171,0.00009785302,0.00004909019,0.0003737349],"genre_scores_gemma":[0.9985821,0.00002579039,0.0001581056,0.00003125991,0.0001467871,0.00001155131,0.00006971958,0.00001257616,0.0009620861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01915966,"threshold_uncertainty_score":0.9989313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02618881092982055,"score_gpt":0.2396074616042993,"score_spread":0.2134186506744787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}