{"id":"W2050728617","doi":"10.1002/pbc.22484","title":"Imatinib mesylate in children and adolescents with cancer","year":2010,"lang":"en","type":"review","venue":"Pediatric Blood & Cancer","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Memorial Sloan-Kettering Cancer Center","keywords":"Medicine; Imatinib; Imatinib mesylate; Myeloid leukemia; Tyrosine-kinase inhibitor; Oncology; Philadelphia chromosome; Tyrosine kinase; Leukemia; Cancer; Platelet-derived growth factor receptor; Internal medicine; Cancer research; Receptor; Chromosomal translocation; Growth factor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002284749,0.0005003948,0.001025991,0.00114913,0.0001466437,0.0003850398,0.0003986229,0.0004541375,0.003600928],"category_scores_gemma":[0.0004010664,0.0001534181,0.0002843685,0.001416631,0.0001571117,0.0005562654,0.0004340746,0.0007365966,0.001192077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002503571,"about_ca_system_score_gemma":0.0005266407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009070132,"about_ca_topic_score_gemma":0.002866733,"domain_scores_codex":[0.999902,0.00002496441,0.0000182586,0.00001473818,0.00003299676,0.000007049281],"domain_scores_gemma":[0.9999105,0.00004078513,0.00002479147,0.000002056837,0.00001347673,0.000008381725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001039672,0.00003431339,0.0002080303,0.02199338,0.0001321791,0.0001946181,0.00004428726,0.0001343707,0.000884027,0.001110346,0.02952615,0.9456342],"study_design_scores_gemma":[0.00009326838,0.00008382752,0.001927974,0.009344236,0.000299625,0.001850095,0.00006344225,0.00006048266,0.0003837218,0.0009733026,0.9849097,0.00001026657],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001311717,0.9989944,0.0000255398,0.00008779629,0.00005185393,0.000004259557,0.00001513736,0.00000275104,0.0006870833],"genre_scores_gemma":[0.001181101,0.9979863,0.0001034338,0.0001618066,0.00005387444,0.000008498914,0.00003502599,6.752666e-7,0.0004693345],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003600928,"threshold_uncertainty_score":0.01204628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01315714555472998,"score_gpt":0.3058714021613215,"score_spread":0.2927142566065915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}