{"id":"W2050746153","doi":"10.1152/jn.00774.2010","title":"Motoneuron Excitability and Muscle Spasms Are Regulated by 5-HT<sub>2B</sub>and 5-HT<sub>2C</sub>Receptor Activity","year":2010,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Agonist; Receptor; 5-HT receptor; Stimulation; Serotonin; Chemistry; Serotonergic; Endocrinology; Internal medicine; Neuroscience; Pharmacology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008323481,0.0002172878,0.0003198765,0.0001535477,0.00008340993,0.0001725184,0.00008324609,0.000223881,0.0006725634],"category_scores_gemma":[0.0001007598,0.0001262956,0.0002376634,0.00009414786,0.0001561581,0.0001177185,0.0001166982,0.0002537813,0.0001505866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002688945,"about_ca_system_score_gemma":0.0001347507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001520215,"about_ca_topic_score_gemma":0.004082479,"domain_scores_codex":[0.999902,0.00001520674,0.00001003843,0.00001675986,0.00002648546,0.00002955901],"domain_scores_gemma":[0.9999354,0.000005939431,0.00002907361,0.000004510361,0.000006994356,0.00001800708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001652443,0.00001169391,0.000819766,0.00002944597,0.00000918371,0.0000365319,0.00001178001,0.00002181954,0.9977609,0.000021347,0.00001351844,0.001098849],"study_design_scores_gemma":[0.00003403807,0.001633117,0.4450586,0.00002737502,0.00008915351,0.0005814481,0.0001147946,0.001134439,0.5499498,0.00007117251,0.00129294,0.00001315048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955413,0.002875159,0.0005582821,0.00003265248,0.000006777999,0.00001590084,0.0001471574,0.00002138447,0.0008014219],"genre_scores_gemma":[0.9968596,0.001532366,0.0004618394,0.00003925392,0.000007506838,0.00003186497,0.0001511383,0.000003894838,0.0009125942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001520215,"threshold_uncertainty_score":0.00302273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00925625043380077,"score_gpt":0.2342752559649529,"score_spread":0.2250190055311521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}