{"id":"W2050863323","doi":"10.1371/journal.pone.0092380","title":"Peptide-Pulsed Dendritic Cells Have Superior Ability to Induce Immune-Mediated Tissue Destruction Compared to Peptide with Adjuvant","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto; Princess Margaret Cancer Centre","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Epitope; Adjuvant; Immune system; Dendritic cell; Cytolysis; CD8; Immunology; Immunotherapy; Adoptive cell transfer; Antigen; Cancer immunotherapy; Biology; Antigen-presenting cell; Cancer research; Cell biology; T cell; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001684462,0.0003295059,0.0003944041,0.0001267263,0.00009744389,0.0003768753,0.0001307346,0.000320214,0.001191804],"category_scores_gemma":[0.0001840211,0.00008688472,0.0001880174,0.0001429357,0.0001542633,0.000200348,0.0001595643,0.0006783372,0.0004417887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001051374,"about_ca_system_score_gemma":0.0001393606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005946107,"about_ca_topic_score_gemma":0.0001128089,"domain_scores_codex":[0.9998286,0.00003359709,0.00001526557,0.00003843757,0.00005176713,0.0000323804],"domain_scores_gemma":[0.9998409,0.00004897975,0.00003646022,0.00002819486,0.00002043841,0.00002509751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000164883,0.00007683071,0.0001346085,0.00006667774,0.000006105255,0.00002922741,0.000005900669,0.00008726917,0.9954542,0.00009282785,0.00003488892,0.003846679],"study_design_scores_gemma":[0.0000280657,0.001183829,0.0007550732,0.000004935113,0.00001848961,0.0002395403,0.000007339006,0.0002573797,0.9952757,0.00006164907,0.002165353,0.000002562335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982554,0.005000283,0.008493876,0.0001215586,0.0001727431,0.00008385973,0.0003620439,0.00009550814,0.003116105],"genre_scores_gemma":[0.9906204,0.001699707,0.004929664,0.00006194994,0.00003960982,0.00004120856,0.0004664304,0.00003070215,0.00211038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191804,"threshold_uncertainty_score":0.003986955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01958129164833447,"score_gpt":0.2270106945056471,"score_spread":0.2074294028573127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}