{"id":"W2050895707","doi":"10.3390/antibiotics3040595","title":"Position-Dependent Influence of the Three Trp Residues on the Membrane Activity of the Antimicrobial Peptide, Tritrpticin","year":2014,"lang":"en","type":"article","venue":"Antibiotics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions; University of Calgary","keywords":"Antimicrobial peptides; Peptide; Antimicrobial; Residue (chemistry); Chemistry; Phosphatidylcholine; Biochemistry; Membrane; Phosphatidylglycerol; Escherichia coli; Peptide sequence; Phospholipid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003876356,0.000205934,0.0003409346,0.00003984599,0.0003992196,0.00001802517,0.0007047727,0.0001972545,0.00004246902],"category_scores_gemma":[0.0002213096,0.0001014757,0.0002419283,0.0001796743,0.001077175,0.00008060747,0.0002503476,0.0004435721,0.00003032259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001917556,"about_ca_system_score_gemma":0.00006798155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005296466,"about_ca_topic_score_gemma":0.0003951316,"domain_scores_codex":[0.9987013,0.00037206,0.0003272769,0.0002243519,0.0000944271,0.0002806055],"domain_scores_gemma":[0.9982131,0.0005178334,0.0004009729,0.0007497975,0.00010786,0.00001039424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001333775,0.0001789064,0.005820581,0.00004951797,0.00009826953,2.770694e-7,0.000172024,0.000332961,0.9858049,0.005607898,0.001615623,0.000185642],"study_design_scores_gemma":[0.0004057833,0.0001153995,0.1031437,0.0002446274,0.00007773057,0.00001583748,0.00005501023,0.000009107621,0.8953593,0.0002205656,0.0002393881,0.0001135351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953152,0.00003102171,0.00004242735,0.002558975,0.0004042093,0.0003415185,0.00008892869,0.00001741458,0.001200291],"genre_scores_gemma":[0.9982136,0.00004688196,0.00002337013,0.0006837543,0.00004054334,2.925779e-7,0.000003428037,0.00001744987,0.0009707048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0973231,"threshold_uncertainty_score":0.4138059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01000839564707228,"score_gpt":0.2130825435919761,"score_spread":0.2030741479449038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}