{"id":"W2050975232","doi":"10.1002/lt.22318","title":"Immunosuppression and hepatocellular carcinoma","year":2011,"lang":"en","type":"review","venue":"Liver Transplantation","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immunosuppression; Sirolimus; Hepatocellular carcinoma; Calcineurin; Medicine; Tacrolimus; Liver transplantation; Cancer research; PI3K/AKT/mTOR pathway; Transplantation; Pharmacology; Immunology; Internal medicine; Signal transduction; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008723941,0.0002852156,0.0003862671,0.00005975885,0.00006210105,0.00001875117,0.0001700892,0.0004021773,0.00004518713],"category_scores_gemma":[0.00000342689,0.0002546077,0.0001627251,0.00005013758,0.00005424697,0.000004928274,0.00002576559,0.0001476009,0.00002166138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001709924,"about_ca_system_score_gemma":0.00009580671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006690513,"about_ca_topic_score_gemma":0.000004695228,"domain_scores_codex":[0.9989318,0.00011507,0.0002636548,0.0004270239,0.00008834524,0.0001741344],"domain_scores_gemma":[0.9994876,0.00001548101,0.0001407751,0.0002677147,0.00003103958,0.00005742026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001876506,0.00007746577,0.0005971515,0.04464941,0.0003827464,0.0002127876,0.0005801385,8.391559e-7,0.008338637,0.0001256263,0.0005380397,0.9443095],"study_design_scores_gemma":[0.0003479602,0.0001752368,0.00009787021,0.003108722,0.001061542,0.0003051753,0.000005129899,0.0000101053,0.006311604,0.00001215571,0.9880889,0.0004756172],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00349572,0.9945797,0.0007653518,8.088922e-7,0.0002238001,0.0003514441,0.0001458006,0.00001449654,0.0004229277],"genre_scores_gemma":[0.005592057,0.9919876,0.0002526391,0.00001669795,0.0001860114,0.00006721026,0.001635647,0.00004990321,0.0002122528],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9875509,"threshold_uncertainty_score":0.9999906,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03208526352511511,"score_gpt":0.2730822921885939,"score_spread":0.2409970286634788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}