{"id":"W2051018861","doi":"10.1016/j.actbio.2013.04.014","title":"Crosslinked collagen hydrogels as corneal implants: Effects of sterically bulky vs. non-bulky carbodiimides as crosslinkers","year":2013,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Corneal Surgery and Treatments","field":"Medicine","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Linköpings Universitet","keywords":"Self-healing hydrogels; Carbodiimide; Biocompatibility; Materials science; Ultimate tensile strength; Collagenase; Biomedical engineering; Cornea; Tissue engineering; Polymer chemistry; Chemistry; Composite material; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001658951,0.0004916877,0.001019319,0.0001553951,0.0001663416,0.0001442519,0.0002464841,0.0003394497,0.0009756852],"category_scores_gemma":[0.0001673963,0.0003994314,0.0002458778,0.0003057202,0.0002932089,0.000231205,0.0001677239,0.00006726471,0.001218587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001283856,"about_ca_system_score_gemma":0.000238011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00565641,"about_ca_topic_score_gemma":0.00002211612,"domain_scores_codex":[0.9974415,0.00005101723,0.0007701167,0.0005888307,0.000434944,0.0007136104],"domain_scores_gemma":[0.9980978,0.0001965076,0.0003608877,0.0006794257,0.000203757,0.0004616504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00170637,0.0004991388,0.0376697,0.0004696704,0.0005201793,0.0005846265,0.0004106511,1.710911e-7,0.9541725,0.000009188319,0.003160581,0.0007972171],"study_design_scores_gemma":[0.003794002,0.001614016,0.217345,0.000308897,0.0002778739,0.0003457714,0.00003872468,0.0000179792,0.7743471,0.0001343364,0.001422873,0.0003534489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951533,0.00005427057,0.000002085607,0.000303879,0.002060964,0.001598087,0.0001075516,0.0001667433,0.0005530953],"genre_scores_gemma":[0.9972337,0.00003942045,0.00009577572,0.0005752028,0.0002201867,0.000183132,0.0002633324,0.00007507853,0.001314158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1798255,"threshold_uncertainty_score":0.9999375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007090416445162112,"score_gpt":0.2562512722982275,"score_spread":0.2491608558530654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}