{"id":"W2051019115","doi":"10.1182/blood-2008-07-170464","title":"The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universität Heidelberg; Stem Cell Network","keywords":"Autocrine signalling; Hepatocyte growth factor; Growth factor; Biology; Receptor; Cell culture; Internal medicine; Cancer research; Endocrinology; Medicine; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000260079,0.0003661278,0.0002984335,0.0005128053,0.0001590461,0.0004074241,0.0002080423,0.0002912348,0.001182909],"category_scores_gemma":[0.000243495,0.0001213928,0.0001684796,0.000345312,0.0002543957,0.0002627381,0.0001979272,0.0003837128,0.0003888721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000359501,"about_ca_system_score_gemma":0.0001729539,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011186,"about_ca_topic_score_gemma":0.001130548,"domain_scores_codex":[0.9998066,0.00004962142,0.00001199074,0.00003966539,0.00004931671,0.00004271255],"domain_scores_gemma":[0.9998325,0.0000590425,0.00003242453,0.00001969955,0.000023184,0.00003309724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009966422,0.00007047897,0.01856857,0.0001723302,0.00002273483,0.0001751845,0.00005155304,0.0002309418,0.9638591,0.00019469,0.0001546251,0.0155031],"study_design_scores_gemma":[0.00005564184,0.002390055,0.144561,0.00003255243,0.0001121571,0.001904797,0.0001538625,0.001702127,0.8374175,0.0002733702,0.01136917,0.00002782374],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710602,0.02418522,0.00221747,0.0001321018,0.00003813759,0.00003763648,0.000672818,0.00006668024,0.001589837],"genre_scores_gemma":[0.9936014,0.002782911,0.001734476,0.00004521875,0.00003869808,0.00002776038,0.0006588626,0.000007581845,0.001103084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001182909,"threshold_uncertainty_score":0.003957212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072917426347173,"score_gpt":0.2628459459420143,"score_spread":0.2521167716785425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}