{"id":"W2051078728","doi":"10.1016/s0006-2952(00)00244-6","title":"Time-dependent changes in brain monoamine oxidase activity and in brain levels of monoamines and amino acids following acute administration of the antidepressant/antipanic drug phenelzine","year":2000,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phenelzine; Monoamine neurotransmitter; Monoamine oxidase; Chemistry; Dopamine; Neurochemical; Norepinephrine; Monoamine oxidase B; Monoamine oxidase inhibitor; Serotonin; Antidepressant; Pharmacology; Internal medicine; Endocrinology; Biochemistry; Medicine; Enzyme; Hippocampus; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002349234,0.0002220749,0.0003894381,0.0001301022,0.00003445856,0.0000114371,0.0002970465,0.0001157956,0.0001348767],"category_scores_gemma":[0.0001014506,0.0001926932,0.00005765957,0.0003418832,0.0004075922,0.0001737487,0.0001160528,0.0002567155,0.000001976102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002643573,"about_ca_system_score_gemma":0.00003439759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002820032,"about_ca_topic_score_gemma":0.00001486337,"domain_scores_codex":[0.9982372,0.0003396892,0.0003707579,0.0005299296,0.0002119875,0.0003104704],"domain_scores_gemma":[0.9991719,0.0004095859,0.0001394631,0.000187287,0.00001361306,0.00007815365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003749437,0.0002835502,0.005490156,0.00003552523,0.000007998278,0.00004655715,0.0002116321,0.000003495774,0.9912269,8.562307e-7,0.0001616992,0.002156725],"study_design_scores_gemma":[0.001655567,0.00008891647,0.07828178,0.00003645249,0.00003694483,0.00003282521,0.000007022662,0.0003203575,0.9193548,0.00001143216,0.00002651004,0.0001473819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964355,0.0001116001,0.000001847485,0.002657385,0.00009360973,0.0005736699,0.00009204303,0.00001940219,0.00001500755],"genre_scores_gemma":[0.9990346,0.00009337575,0.00002556196,0.0005907543,0.00002317299,0.00004423141,0.000001448162,0.0000191652,0.0001676456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07279162,"threshold_uncertainty_score":0.78578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02281347223645135,"score_gpt":0.3101600754116699,"score_spread":0.2873466031752185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}