{"id":"W2051078728","doi":"10.1016/s0006-2952(00)00244-6","title":"Time-dependent changes in brain monoamine oxidase activity and in brain levels of monoamines and amino acids following acute administration of the antidepressant/antipanic drug phenelzine","year":2000,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phenelzine; Monoamine neurotransmitter; Monoamine oxidase; Chemistry; Dopamine; Neurochemical; Norepinephrine; Monoamine oxidase B; Monoamine oxidase inhibitor; Serotonin; Antidepressant; Pharmacology; Internal medicine; Endocrinology; Biochemistry; Medicine; Enzyme; Hippocampus; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001954703,0.000576866,0.0008696247,0.0003623962,0.0002423664,0.0004132848,0.0003131692,0.0005408958,0.002700235],"category_scores_gemma":[0.0006948797,0.000393645,0.0004089313,0.0003684699,0.0008337108,0.0005834742,0.0002058874,0.001909829,0.0004386076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005300463,"about_ca_system_score_gemma":0.0004731693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002069588,"about_ca_topic_score_gemma":0.005814996,"domain_scores_codex":[0.9998595,0.00001586099,0.000009670772,0.00002395919,0.00002877047,0.00006227314],"domain_scores_gemma":[0.9993631,0.0002028971,0.0001390641,0.00006263463,0.00006730168,0.0001650351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.07706225,0.001431073,0.004210392,0.0001950002,0.000197703,0.0005422218,0.0002678549,0.0002364932,0.9010491,0.0003266234,0.000592582,0.01388859],"study_design_scores_gemma":[0.000796119,0.01658689,0.1222862,0.00002990246,0.000340739,0.0004865385,0.0002784489,0.002160643,0.8550733,0.0003271856,0.001562795,0.00007133986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964652,0.000779392,0.0007240279,0.0001501697,0.0001378517,0.00004813575,0.0007374327,0.00005819683,0.0008995908],"genre_scores_gemma":[0.9929755,0.001032427,0.0006511566,0.0001312578,0.00006429291,0.0001096569,0.001373283,0.00002165744,0.003640896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002700235,"threshold_uncertainty_score":0.009033203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02281347223645135,"score_gpt":0.3101600754116699,"score_spread":0.2873466031752185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}